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Clinical Trial to Determine the MTD of HM781-36B in Patients With Advanced Solid Tumors

Advanced Solid Malignancies Clinical Trial

Official title:
Phase Ⅰ Study to Determine the Maximum Tolerated Dose of HM781-36B Continuously Given in Patients With Advanced Solid Tumors and to Assess the Food Effect on Pharmacokinetic Profile

Clinical Trial Summary

The main objective of this study is to determine the maximum tolerated dose (MTD) of HM781-36B continuously.

Clinical Trial Description

Besides the main objective, there are 4 other objectives as follows:

1. To determine dose-limiting toxicity (DLT) of HM781-36B

2. To determine Maximum Tolerated Dose (MTD) of HM781-36B

3. To determine the effect of food on the pharmacokinetics after dosed HM781-36B continuously

4. To evaluate anticancer activity of HM781-36B in patients with advanced solid malignancies ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01455584
Study type Interventional
Source Hanmi Pharmaceutical Company Limited
Contact
Status Completed
Phase Phase 1
Start date June 2011
Completion date May 2013
View Details
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