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Advanced Solid Malignancies clinical trials

View clinical trials related to Advanced Solid Malignancies.

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NCT ID: NCT05469919 Active, not recruiting - Clinical trials for Advanced Solid Malignancies

An Open-Label Phase 1 Study of Ceralasertib in Japanese Patients With Advanced Solid Malignancies

Start date: June 9, 2022
Phase: Phase 1
Study type: Interventional

This is a Phase 1, open-label study designed to evaluate the safety, tolerability, pharmacokinetics, and anti-tumor activity of ceralasertib in Japanese patients with advanced solid malignancies. Cycle 0 duration is 4 days and each cycle from Cycle 1 has a duration of 28 days.

NCT ID: NCT04606381 Active, not recruiting - Clinical trials for Advanced Solid Malignancies

A Study of Amivantamab Subcutaneous (SC) Administration for the Treatment of Advanced Solid Malignancies

PALOMA
Start date: November 10, 2020
Phase: Phase 1
Study type: Interventional

The purpose of this study is to assess the feasibility of subcutaneous (SC) administration of amivantamab based on safety and pharmacokinetics and determine a dose, dose regimen and formulation for amivantamab SC delivery.

NCT ID: NCT02398747 Active, not recruiting - Clinical trials for Advanced Solid Malignancies

Japanese Phase I Study of AZD2014 in Advanced Solid Malignancies

Start date: March 17, 2015
Phase: Phase 1
Study type: Interventional

The primary objective of this study is to investigate the safety and tolerability of continuous and/or intermittent dosing of AZD2014 when given orally to patients with advanced solid malignancies.