High Risk Pregnancy Clinical Trial
Official title:
University Hospital Advanced Age Pregnant Cohort
The University Hospital Advanced Age Pregnant (UNIHOPE) Cohort is the major part of the National Key Research and Development Program on Reproductive Health & Major Birth Defects Control and Prevention Project, which is funded by the Ministry of Science and Technology of China. The Project is led by Prof. Zhao Yangyu, from the Department of Gynecology & Obstetrics, Peking University Third Hospital, and the UNIHOPE cohort is led by Prof. Jian-meng Liu, the Co-PI of the Project.
The UNIHOPE Cohort is set up to provide comprehensive evidence for the prevention and treatment of gestational complications in pregnant women with advanced maternal age, and therefore, to meet the growing clinical challenges of increasing pregnant women with advanced age in the two-child era. The UNIHOPE Cohort is planning to recruit 22,000 pregnant women aged ≥35 years from 9 large obstetrical center of major University-affiliated Hospitals across China, between July 2016 and December 2020. All women will be enrolled prior to 14 wks of gestation, followed up at 24-28 wks, 32-34 wks of gestation, delivery, and 42 days postpartum. Data including demographics, medical history, reproductive history, prenatal health care, gestational complications, and pregnancy and birth outcomes will be collected via electronic data capture system. Venous blood of the pregnant women will be collected at enrollment and each follow-up visit during pregnancy, and placental tissue, cord blood and hair of the newborn will also be collected. ;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT02627482 -
Ambulatory Fetal Heart Rate Monitoring in Small Babies
|
N/A | |
| Active, not recruiting |
NCT03904979 -
Therapeutic Writing to Reduce Stress
|
N/A | |
| Completed |
NCT02749851 -
Placenta Imaging Project
|
||
| Completed |
NCT03772080 -
Prematurity Education in High Risk Pregnancies
|
N/A | |
| Recruiting |
NCT06151613 -
Continuous Non-invasive Electrophysiological Monitoring in High Risk Pregnancies
|
N/A | |
| Recruiting |
NCT05763069 -
HOME: Home Monitoring of High-risk Pregnancies
|
||
| Completed |
NCT01708746 -
Investigation of the Impact of Noninvasive Prenatal Testing for Fetal Aneuploidy on Utilization of Prenatal Diagnostic Procedures and Pregnant Women's Views
|
N/A | |
| Not yet recruiting |
NCT04173559 -
Sleep and Tracking Effects in Pregnancy Study
|
N/A | |
| Recruiting |
NCT03152058 -
IMPACT Study: IMProve Pregnancy in APS With Certolizumab Therapy
|
Phase 2 | |
| Not yet recruiting |
NCT06320054 -
Preventing Obstetric Complications With Dietary Intervention
|
N/A | |
| Not yet recruiting |
NCT04855513 -
Prevention of Pre-eclampsia Using Metformin: a Randomized Control Trial
|
N/A | |
| Completed |
NCT03082664 -
Negative Pressure Wound Therapy to Prevent Wound Complications Following Cesarean Section in High Risk Patients
|
N/A | |
| Recruiting |
NCT06279559 -
Music Therapy and High-risk Pregnancy
|
N/A | |
| Not yet recruiting |
NCT05479357 -
Carbetocin Versus Oxytocin for Prophylaxis Against Atonic Primary Post-partum Hemorrhage
|
N/A | |
| Recruiting |
NCT04203082 -
Cognitive Behavioral Intervention to Reduce Procedural Anxiety Among Woman With High Risk Pregnancies With Scheduled Cesarean Deliveries
|
N/A | |
| Completed |
NCT02379351 -
Use Of An In-Home Non-Stress Test Device For Remote Fetal Monitoring
|
N/A | |
| Recruiting |
NCT04783597 -
Early Prediction of Preeclampsia Using arteriaL Stiffness in High-risk prEgnancies
|
||
| Recruiting |
NCT06130150 -
Sexual Function in High-risk Pregnant Women
|
||
| Recruiting |
NCT03775954 -
Fetal Electrophysiologic Abnormalities in High-Risk Pregnancies Associated With Fetal Demise
|
||
| Suspended |
NCT02838030 -
Efficacy of Aspirin and L-arginine in High Risk Preeclamptic
|
Phase 2 |