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Clinical Trial Summary

To explore the efficacy and safety of Cetuximab in combination with dabrafenib and Tislelizumab in BRAF mutated treatment of advanced colorectal cancer


Clinical Trial Description

Due to Encorafenib has not been marketed in China, it is difficult to benefit patients, and there are no reported studies of Dabrafenib, also a BRAF inhibitor, in combination with anti-EGFR monoclonal antibody and immunotherapy in BRAF mutated mCRC. Therefore, we intend to use Dabrafenib in combination with cetuximab and Tislelizumab in the treatment of BRAF V600E mutated patients with advanced colorectal cancer to observe the initial efficacy and safety. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05963087
Study type Interventional
Source Zhejiang Cancer Hospital
Contact Wangxia Lv
Phone 13757141026
Email lvwangxia@163.com
Status Not yet recruiting
Phase N/A
Start date August 2023
Completion date June 2026

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