Clinical Trials Logo

Advanced Cancers clinical trials

View clinical trials related to Advanced Cancers.

Filter by:

NCT ID: NCT01193530 Terminated - Advanced Cancers Clinical Trials

The Use of Light Therapy for Managing Sleep Disturbances in Patients With Advanced Cancer

Start date: June 2011
Phase: Phase 2/Phase 3
Study type: Interventional

The goal of this research study is to learn if a type of light therapy can be used to help patients with advanced cancer who are having difficulty sleeping to sleep better.

NCT ID: NCT01183663 Completed - Advanced Cancers Clinical Trials

Lenalidomide in Combination With Bevacizumab, Sorafenib, Temsirolimus, or 5-Fluorouracil, Leucovorin, Oxaliplatin (FOLFOX)

Start date: August 2010
Phase: Phase 1
Study type: Interventional

The goal of this clinical research study is to find the highest tolerable doses of the combinations of lenalidomide and other drugs that can be given to patients with advanced cancer. The safety of the drug combinations will also be studied.

NCT ID: NCT01178112 Completed - Advanced Cancers Clinical Trials

Trientine and Carboplatin in Advanced Malignancies

Start date: July 2010
Phase: Phase 1
Study type: Interventional

The goal of this clinical research study is to find the highest tolerable dose of the combination of trientine and carboplatin that can be given to patients with advanced cancer. The safety of this drug combination will also be studied.

NCT ID: NCT01087983 Completed - Advanced Cancers Clinical Trials

Lapatinib With Sirolimus or Metformin

Start date: March 2010
Phase: Phase 1
Study type: Interventional

The goal of this clinical research study is to find the highest tolerable dose of 2 different combinations of drugs that can be given to patients with advanced cancer. The first combination of drugs is Tykerb (lapatinib) and Rapamune (sirolimus), and the second combination is lapatinib and Glucophage (metformin). The safety of these drug combinations will also be studied.

NCT ID: NCT01057264 Completed - Advanced Cancers Clinical Trials

HAI Abraxane With Gemcitabine and Bevacizumab

Start date: January 2010
Phase: Phase 1
Study type: Interventional

The goal of this clinical research study is to find the highest tolerable dose of Abraxane® (nab-paclitaxel) when given directly into the liver, in combination with Gemzar® (gemcitabine) and Avastin® (bevacizumab) when given by vein.

NCT ID: NCT01024166 Completed - Advanced Cancers Clinical Trials

Patient-Reported Outcomes-Based Palliative and Hospice Care Practice: A Usability Study

Start date: November 2009
Phase: N/A
Study type: Observational

The goal of this research study is to learn if palliative care patients or caregivers, and palliative care physicians or nurses can use a computer program designed to provide information about the symptoms and overall health of cancer patients.

NCT ID: NCT01021072 Completed - Advanced Cancers Clinical Trials

A First in Man Study of MABp1 in Patients With Advanced Cancers

Start date: March 31, 2010
Phase: Phase 1
Study type: Interventional

The purpose of this study is to block interleukin-1 alpha activity with a True Human monoclonal antibody, thus interrupting the inflammatory response that supports tumor growth/metastasis and which drives the cachexic process. An adaptive design will be employed which will allow for the exploration of different dosing regimens, as well as tumor types that show preliminary evidence of efficacy.

NCT ID: NCT01011140 Recruiting - Dehydration Clinical Trials

Physician Perceptions About Parenteral Hydration in Latin America and Spain

Start date: January 2010
Phase:
Study type: Observational

The purpose of this study is to assess palliative care physicians' attitudes, beliefs and practice patterns related to parenteral hydration at the end of life in Latin America and Spain. Objectives: 1. To assess palliative care physicians' attitudes, beliefs and practice patterns related to parenteral hydration at the end of life in Latin America and Spain. 2. To assess cross-national differences in practice patterns related to parenteral hydration at the end of life. (Latin America vs. Spain). 3. To determine the percentage of physicians who practice parenteral hydration at the end-of-life in the hospital setting and the home setting. 4. To examine the association between providers' parenteral hydration practice patterns and: - 1. provider demographic characteristics; - 2. specific characteristics of their practice settings; and - 3. training and experience in end of life care; 5. To determine which factors most predict the practice of parenteral hydration at the end of life among palliative care physicians.

NCT ID: NCT01003626 Withdrawn - Melanoma Clinical Trials

Interstitial Fluid Pressure (IFP) Pilot Study in Melanoma Patients

Start date: March 2010
Phase: N/A
Study type: Interventional

The goal of this clinical research study is to learn about the side effects of measuring the tumor pressure in patients who have advanced melanoma and have not received chemotherapy. Researchers also want to learn if patients with a lower tumor pressure may respond better to chemotherapy.

NCT ID: NCT00941499 Completed - Advanced Cancers Clinical Trials

Hepatic Arterial Infusion Oxaliplatin + 5FU, Leucovorin, and Bevacizumab +/- Cetuximab

Start date: July 2009
Phase: Phase 1
Study type: Interventional

The goal of this clinical research study is to find the best combination of oxaliplatin, bevacizumab, 5-fluorouracil, leucovorin, and cetuximab that can be given to patients with advanced cancer that has spread to the liver. Different combinations of these drugs will be used, and the safety of all drug combinations will also be studied.