Advanced Cancer Clinical Trial
Official title:
Prognostic Understanding in Patients Receiving Enhanced Supportive Care (ProgESC Study)
This study aims to assess how aware patients with advanced cancer are about their prognosis when they are referred to an Enhanced Supportive Care (ESC) service. Further, the study aim to assess the relationship between patients prognostic understanding and their mental health, quality of life, trust in medical professionals as well as their perception of the care they receive. The study will involve adult patients with advanced cancer who are referred to the ESC service at London University College Hospital. Patients who agree to participate will provide consent and answer a questionnaire. The questionnaire will cover their prognostic awareness, psychological symptoms, and quality of life. It takes about 20 minutes to complete and can be done online via RedCap
Status | Not yet recruiting |
Enrollment | 100 |
Est. completion date | October 31, 2024 |
Est. primary completion date | August 31, 2024 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 18 Years and older |
Eligibility | Inclusion Criteria: - All participants aged 18 and older with advanced cancer referred to the ESC team will be eligible for this study. Exclusion Criteria: - Younger than 18 years - Insufficient English language to complete questionnaires - cognitive impairment - Participants who, in the opinion of the member of the ESC team, would not be appropriate to participate |
Country | Name | City | State |
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n/a |
Lead Sponsor | Collaborator |
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University College, London |
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* Note: There are 28 references in all — Click here to view all references
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Other | Symptoms of anxiety | Patients' symptoms of anxiety assessed through the Generalized Anxiety Disorder 2-item. This scale has a range from 0 to 6 points with higher scores indicating more symptoms of anxiety. A score of 3 points is considered a cut-off point, in which further evaluation is recommended. | within 1 week after patient assessment by the Enhanced Supportive Care Team | |
Other | Symptoms of depression | Patients' symptoms of depression assessed through the Patient Health Questionnaire-2. This scale has a range from 0 to 6 points with higher scores indicating more depressive symptoms. A score of 3 points is considered a cut-off point, in which further evaluation is recommended. | within 1 week after patient assessment by the Enhanced Supportive Care Team | |
Other | Patients' quality of life | Patients' quality of life assessed through the European Organisation for Research and Treatment of Cancer quality of life core 15 palliative questionnaire. This 15-item questionnaire, employs a 4-point Likert scale for each question, and the resulting scores are linearly transformed to a possible range of 0 to 100, where higher scores indicate a better quality of life | within 1 week after patient assessment by the Enhanced Supportive Care Team | |
Other | Trust in the treating oncologist | Patients' trust in the treating oncologist assessed on a numeric rating scale ranging from 0-10 with higher scores indicating more trust | within 1 week after patient assessment by the Enhanced Supportive Care Team | |
Other | Satisfaction with care | Patients' satisfaction with care assessed on a numeric rating scale ranging from 0-10 with higher scores indicating greater satisfaction | within 1 week after patient assessment by the Enhanced Supportive Care Team | |
Primary | Patients' prognostic understanding | Patients' prognostic understanding about their illness assessed through the Prognosis and Treatment Perception Questionnaire. This questionnaire assesses patient beliefs regarding the likelihood of cure, the preference for receiving prognostic information as well as the perceived helpfulness of knowing about prognosis | within 1 week after patient assessment by the Enhanced Supportive Care Team | |
Secondary | Perceived value of prognostic information | Assessed through the Prognosis and Treatment Perception Questionnaire. This questionnaire assesses patient beliefs regarding the likelihood of cure, the preference for receiving prognostic information as well as the perceived helpfulness of knowing about prognosis | within 1 week after patient assessment by the Enhanced Supportive Care Team |
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