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Clinical Trial Summary

This is a early Phase 1 open-label study to explore the safety and possible efficacy of EX02 CAR T cell therapy in the treatment of patients with unresectable and/or metastatic pancreatic/bile duct cancer. Each participant will undergo leukapheresis after enrolment, receive treatment of the conditioning chemotherapy of cyclophosphamide and fludarabine, and an intra-tumoral injection or intraperitoneal infusion of Ex02 CAR T cells, probably followed by an intravenous infusion of EX02 CAR T cells. Each participant will proceed through the following study procedures: - Screening - Enrollment/Leukapheresis - Conditioning chemotherapy - CAR T treatment - Post-treatment assessment - Long-term follow-up


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT06196658
Study type Interventional
Source First People's Hospital of Hangzhou
Contact Xiaofeng Zhang
Phone 057156005600
Email zxf837@tom.com
Status Not yet recruiting
Phase Early Phase 1
Start date January 1, 2024
Completion date December 31, 2027

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