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NCT ID: NCT04832607 Recruiting - Clinical trials for Stem Cell Transplant Complications

Multivirus-specific T-cell Transfer Post SCT vs AdV, CMV and EBV Infections

TRACE
Start date: August 27, 2019
Phase: Phase 3
Study type: Interventional

Haematopoietic stem cell transplantation (HSCT) can expose patients to a transient but marked immunosuppression, during which viral infections are an important cause of morbidity and mortality. Adoptive transfer of virus-specific T cells is an attractive approach to restore protective T-cell immunity in patients with refractory viral infections after allogeneic HSCT. The aim of this Phase III trial is to confirm efficacy of this treatment in children and adults.