Evaluation of a Dry Powder Aerosol Dispersion Mechanism by Radiolabeling Techniques — DPI

Adult Healthy Volunteers Clinical Trial

Official title:
Evaluation of a Dry Powder Aerosol Dispersion Mechanism by Radiolabeling Techniques

Status Completed

Clinical Trial Summary

The primary objective is to admix a radiolabel with albuterol sulphate for incorporation into the Handihaler® device for inhalation studies. This will allow for the investigators to determine the regional lung deposition of drug inhaled from the standard Handihaler® device compared to a novel modification of the device to provide more effective dispersion and aerosolization of the coated albuterol powder. The new mechanism of action for proof-of-concept testing consists of a bead (5.1 mm; expanded polystyrene foam) coated with drug powder, as opposed to the standard lactose formulation-filled capsule.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Adult Healthy Volunteers

Clinical Trial Details

NCT number	NCT01495442
Study type	Interventional
Source	University of North Carolina, Chapel Hill
Contact
Status	Completed
Phase	N/A
Start date	December 2011
Completion date	June 2012

View Details

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