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NCT05817734 Clinical Trial

Human Phenotype Project Study Protocol

Adult Disease Clinical Trial

Official title:
Longitudinal Collection of Observational Clinical and Lifestyle Data

Clinical Trial Details — Status: Recruiting

Administrative data
NCT number NCT05817734
Other study ID # 1789-1
Secondary ID
Status Recruiting
Phase
First received
Last updated
Start date October 1, 2018
Est. completion date December 31, 2045

Study information
Verified date April 2023
Source Weizmann Institute of Science
Contact Eran Segal, Prof.
Phone 972-8-9343266
Email Eran.Segal@weizmann.ac.il
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

This is a prospective study aimed at recruiting 30,000 individuals, aged 40-70 years old, and following them longitudinally for 25 years with repeated measurements. The basic follow-up frame will include a visit to the Clinical Test Center (CTC) every two years and a phone interview every other year (on uneven years). Sample collection and biobanking will be performed every two years and online questionnaires will be filled out on an annual basis. The primary goals are to study the variation observed across different individuals in disease susceptibility, clinical phenotypes, and therapeutic responses. The study aims at studying the complex interplay and relative contribution of different omics, physiological characteristics and lifestyle on disease pathogenesis and progression and to evaluate how these effects are mediated.

Recruitment information / eligibility
Status Recruiting
Enrollment 30000
Est. completion date December 31, 2045
Est. primary completion date December 31, 2045
Accepts healthy volunteers Accepts Healthy Volunteers
Gender All
Age group 18 Years and older
Eligibility Inclusion Criteria: - Ages 18+, males and females. Exclusion Criteria: - Pregnancy. - Mentally disabled or in general legally non-competent. - Prisoner or soldier. Soldiers: mandatory service only - Active cancer - Fertility Treatments (current) - Hepatitis ( B, C), chronic or acute - HIV - Liver cirrhosis - Dialysis - Unstable medical conditions

Study Design

Related Conditions & MeSH terms

Locations
Country Name City State
Israel Weizmann institute of science Re?ovot

Sponsors (1)
Lead Sponsor Collaborator
Weizmann Institute of Science

Country where clinical trial is conducted

Israel, 

Outcome
Type Measure Description Time frame Safety issue
Primary Adult disease Development of medical conditions based on participant's self-reporting coded to ICD11. 25 years
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