Outcome
Type |
Measure |
Description |
Time frame |
Safety issue |
Primary |
Muscle quality sarcopenia |
Sarcopenia will be assessed taking into account the reference values established for muscle quality. The muscle quality will be measure by hand grip strength test. This test will be performance with manual dynamometry (TKK 5401; Scientific Instruments Co., Ltd., Tokyo, Japan). Maximal isometric upper limb strength will be performance by maximal isometric strength. Upper strength will be register by kilogrammes. Higher value show high strength. |
Changes from baseline to 8 weeks |
|
Secondary |
Change Body composition |
Body composition will be assessed by dual energy X-ray absorptiometry (DEXA). This is noninvasive technique. The result will be register in absolutes and percentages results. |
Changes from baseline to 8 weeks |
|
Secondary |
Change Blood pressure |
Blood pressure and heart rate will be assessed by means of an automatic device (Colin BP 880, Inc., Tampa, FL). This is noninvasive technique. The result will be register in millimeters of mercury (bood pressure) and number of pulse per minutes (heart rate). |
Changes from baseline to 8 weeks |
|
Secondary |
Change Chair stand test |
Chair stand test measure the functional capacity. This is a easy physical test. This test measures the functionality of getting up and sitting down from a chair five times. The participant have to performance the test as faster as possible. The total time is recorded in seconds. A better time indicates better functional ability. |
Changes from baseline to 8 weeks |
|
Secondary |
Change Upper strength |
Maximal isometric upper limb strength will be performance by maximal isometric strength of knee extension and biceps flexion with load cell. Maximal isometric lower limb will be registered in newton. Higher value show high strength. |
Changes from baseline to 8 weeks |
|
Secondary |
Change Sagittal spinal curvature |
Sagittal spinal curvature will be assess with the Spinal Mouse device (Switzerland). It will be measured: angle of the dorsal and lumbar curve and pelvic tilt when standing and in asthenic sitting. This is noninvasive technique. The result is register in grades. |
Changes from baseline to 8 weeks |
|
Secondary |
Health-related quality |
Health-related quality of life will be assessed by means of the Short Form 36 questionaire. This questionaire have 11 questions and show result for 9 area: physical role, pain, general health, vitality, social function, emotional role, mental health, and evolution of the health care system. Each area is reported from 0 to 100 point. Higher score represent better health-related quality. |
Changes from baseline to 8 weeks |
|
Secondary |
Satisfaction with Life Scale (SWL) |
Satisfaction with Life Scale (SWL) questionnaires include 5 affirmation about the satisfaction with the life and the participant have to answers from strongly agree to strongly disagree. The final score is reported from 5 to 35 point. Higher value show better satisfaction with life. |
Changes from baseline to 8 weeks |
|
Secondary |
Adherence to the Mediterranean diet |
It will be used the Adherence to the Mediterranean diet. This questionaire have 14 questions (yes and no answer) about their adherence to the mediterranean diet. The sum of the answers are collect. Higher score show higher adherence to mediterranean diet. |
Changes from baseline to 8 weeks |
|
Secondary |
Functional competence 400 meter walk |
Functional competence 400 meter walk is a test included in the European Consensus (EWGSOP2) to measure sarcopenia. Participant have to walk as fast as possible 400 meter. The total time is register. |
Changes from baseline to 8 weeks |
|
Secondary |
Change bone mineral density |
Bone mineral density will be assessed by dual energy X-ray absorptiometry (DEXA). This is noninvasive technique. The result will be register in absolutes and percentages results. |
Changes from baseline to 8 weeks |
|
Secondary |
Change heart rate |
Heart rate will be assessed by means of an automatic device (Colin BP 880, Inc., Tampa, FL). This is noninvasive technique. The result will be register in number of pulse per minutes (heart rate). |
Changes from baseline to 8 weeks |
|
Secondary |
Gait speed change |
Gait speed will be measure by 4. 6 and 10 meter test. This is easy physical test in with the participant have to walk 4. 6 and 10 metres as faster as possible. The result will be register in seconds. Less time indicates better functional ability. |
Changes from baseline to 8 weeks |
|
Secondary |
Time up and go test change |
Time up and go test measure the functional capacity of getting up, walking and sitting down form a chair. Participant have to performance this test as faster as possible. This is a easy physical test. Total seconds are records. Less seconds indicates better functional ability. |
Changes from baseline to 8 weeks |
|
Secondary |
Short physical performance battery (SPPB) |
Short physical performance battery (SPBB) include three test (balance, chair stand test and gait speed) and report a final score. Chair stand test and gait speed were describe in other outcome. Balance test is a easy physical test. The participant must maintain three balancing positions for 10 seconds to overcome it. Each test offers a different score. Higher score show better functional capacity. |
Changes from baseline to 8 weeks |
|
Secondary |
Change in lower limb strenght |
Maximal isometric lower limb will be performance by maximal isometric strength of knee extension with load cell. Maximal isometric lower limb will be registered in newton. Higher value show high strength. |
Changes from baseline to 8 weeks |
|