Adult Acute Lymphocytic Leukemia Clinical Trial
Official title:
A Phase-2 Clinical Study to Determine the Efficacy and Safety of Depocyt (Cytarabine Liposome Injection) for the Treatment of CNS Relapse in Adult Patients With Acute Lymphoblastic Leukemia or Very Aggressive Lymphoma
Patients with acute lymphoblastic leukaemia or very aggressive lymphoma and documented isolated CNS relapse or CNS relapse combined with other relapse sites should receive therapy with intrathecal DepoCyte at least once. Treatment may be repeated during induction phase each 2 weeks and monthly during maintenance phase. The study aim is to replace the usual 2-3 weekly applications of intrathecal triple therapy with one application of DepoCyte. Primary objective is the response rate after one application of DepoCyte. Further objectives are the compilation of data regarding safety and toxicity
n/a
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT00199056 -
German Multicenter Trial for Treatment of Newly Diagnosed Acute Lymphoblastic Leukemia in Adults (06/99)
|
Phase 4 | |
| Completed |
NCT00199043 -
Treatment of Hyperuricemia With Rasburicase in Patients With Acute Lymphoblastic Leukemia or High Grade Lymphoma
|
Phase 3 | |
| Completed |
NCT00198978 -
German Multicenter Trial for Treatment of Elderly Patients With Newly Diagnosed Acute Lymphoblastic Leukemia
|
Phase 4 | |
| Completed |
NCT00199095 -
Treatment of Elderly Patients (>65 Years) With Acute Lymphoblastic Leukemia
|
Phase 4 | |
| Completed |
NCT00199004 -
Trial for Treatment of Adult Patients With Standard Risk Acute Lymphoblastic Leukemia With Chemotherapy and Rituximab
|
Phase 4 | |
| Completed |
NCT00198991 -
German Multicenter Trial for Treatment of Newly Diagnosed Acute Lymphoblastic Leukemia in Adults (07/2003)
|
Phase 4 | |
| Completed |
NCT00199069 -
German Multicenter Trial for Treatment of Newly Diagnosed Acute Lymphoblastic Leukemia in Adults (05/93)
|
Phase 4 |