Side-specific Factors for Conversion in Adrenalectomy for Pheochromocytoma.

Adrenal Tumor Clinical Trial

Official title:

Side-specific Factors for Conversion in Adrenalectomy for Pheochromocytoma. A Comparative Analysis

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT06330558
• Other study ID #: pheos
• Status: Completed
• Start date: September 1, 2016
• Est. completion date: September 1, 2023

Study information

• Verified date: March 2024
• Source: Zagazig University
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Context: Adrenalectomy for pheochromocytoma (PHEO) poses difficulties due to the elevated chance of conversion. The objective of this study was to conduct a comparative analysis of the occurrence and determinants of conversion in left-sided abdominal laparoscopic adrenalectomy (LLA) and right-sided abdominal laparoscopic adrenalectomy (RLA). Methods: A retrospective analysis was conducted to include a total of 271 patients diagnosed with PHEO. These patients were separated into two groups: LRA (N=121) and LLA (N=150). The study period spanned from September 2016 to September 2023.

Description:

The process of performing an adrenalectomy for pheochromocytoma (PHEO) is difficult due to the significant risk of conversion. The objective of this study was to conduct a comparative analysis of the occurrence and determinants of conversion in left-sided abdominal laparoscopic adrenalectomy (LLA) and right-sided abdominal laparoscopic adrenalectomy (RLA). Methods: A retrospective analysis was conducted to include a total of 271 patients diagnosed with PHEO. These patients were separated into two groups: LRA (N=121) and LLA (N=150). The study period spanned from September 2016 to September 2023.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 271
• Est. completion date: September 1, 2023
• Est. primary completion date: September 1, 2023
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Unilateral pheochromocytoma of any size, over 18 years old, both males and females

Exclusion Criteria:

• Patients undergoing initial open adrenalectomy, - Additional surgical interventions during total laparoscopic adrenalectomy, - Partial adrenalectomy, Bilateral PHEOS. Hemorrhagic diathesis, Structural deformity Pregnancy,
• Prior unilateral abdominal surgery, data is absent. The preoperative diagnosis is ambiguous. Hereditary (PHEO), or recurrent PHEO

Related Conditions & MeSH terms

• Adrenal Gland Neoplasms
• Adrenal Tumor
• Pheochromocytoma

Intervention

Procedure:
• laparoscopic right adrenalectomy
adrenalectomy

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Zagazig University

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	conversion	number of conversion	intraoperative