Metabolic Syndrome Clinical Trial
Official title:
Endocrine, Bone And Metabolic Disorders In Adults After Allogeneic Stem-cell Transplant
Allogeneic hematopoietic stem cell transplantations (allo-HSCT) is often indicated in
malignant hematologic diseases. Conditioning regimens, used to reduce the tumor burden and to
prevent transplant rejection, are based on chemotherapy alone or combined with total body
irradiation (TBI). Endocrine complications are frequent transplant-related side effects.
Investigators have been well described in children studies but less in adulthood.
The objective of this study is to assess retrospectively endocrine, bone and metabolic
disorders in adult patients, 12 months after allo-HSCT.
Patients & Methods Inclusion criteria are : patients treated with allo-HSCT from 2006 to 2016
for a malignant hematologic disease; adult and in complete remission at exploration.
Exclusion criteria are : anteriority of brain radiotherapy and prior HSCT.
Twelve months after HSCT, each patient underwent fasting measurement of IGF1, TSH, fT4, FSH,
LH, sex steroids, glycemia, insulin level, and lipid profile. Unless contraindication,
adrenal and growth hormone functions were assessed with insulin hypoglycemia test. A dual
X-ray absorptiometry was also performed.
Investigators will assess the prevalence of endocrine, bone and metabolic disorders 12 months
after allo-HSCT and describe some of their risk factors.
;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Recruiting |
NCT04635202 -
Effect of Elliptical Training on Metabolic Homeostasis in Metabolic Syndrome
|
N/A | |
| Completed |
NCT05343858 -
Pilot Study to Evaluate the Effect of Two Microalgae Consumption on Metabolic Syndrome
|
N/A | |
| Completed |
NCT04053686 -
An Intervention to Reduce Prolonged Sitting in Police Staff
|
N/A | |
| Active, not recruiting |
NCT05891834 -
Study of INV-202 in Patients With Obesity and Metabolic Syndrome
|
Phase 2 | |
| Recruiting |
NCT05040958 -
Carotid Atherosclerotic Plaque Load and Neck Circumference
|
||
| Completed |
NCT03644524 -
Heat Therapy and Cardiometabolic Health in Obese Women
|
N/A | |
| Active, not recruiting |
NCT02500147 -
Metformin for Ectopic Fat Deposition and Metabolic Markers in Polycystic Ovary Syndrome (PCOS)
|
Phase 4 | |
| Recruiting |
NCT03227575 -
Effects of Brisk Walking and Regular Intensity Exercise Interventions on Glycemic Control
|
N/A | |
| Recruiting |
NCT05972564 -
The Effect of SGLT2 Inhibition on Adipose Inflammation and Endothelial Function
|
Phase 1/Phase 2 | |
| Completed |
NCT03289897 -
Non-invasive Rapid Assessment of NAFLD Using Magnetic Resonance Imaging With LiverMultiScan
|
N/A | |
| Recruiting |
NCT05956886 -
Sleep Chatbot Intervention for Emerging Black/African American Adults
|
N/A | |
| Completed |
NCT06057896 -
Effects of Combined Natural Molecules on Metabolic Syndrome in Menopausal Women
|
||
| Active, not recruiting |
NCT03613740 -
Effect of Fucoxanthin on the Metabolic Syndrome, Insulin Sensitivity and Insulin Secretion
|
Phase 2 | |
| Completed |
NCT04498455 -
Study of a Prebiotic Supplement to Mitigate Excessive Weight Gain Among Physicians in Residency
|
Phase 4 | |
| Completed |
NCT05688917 -
Green Coffee Effect on Metabolic Syndrome
|
N/A | |
| Completed |
NCT04117802 -
Effects of Maple Syrup on Gut Microbiota Diversity and Metabolic Syndrome
|
N/A | |
| Completed |
NCT03697382 -
Effect of Daily Steps on Fat Metabolism
|
N/A | |
| Completed |
NCT03241121 -
Study of Eating Patterns With a Smartphone App and the Effects of Time Restricted Feeding in the Metabolic Syndrome
|
N/A | |
| Completed |
NCT04509206 -
Virtual Teaching Kitchen
|
N/A | |
| Completed |
NCT05124847 -
TREating Pediatric Obesity
|
N/A |