Does Inhaled Busedonide or Fluticasone Impair Adrenal Function?

Status Terminated

Clinical Trial Summary

Inhaled corticosteroids are largely used in patients with asthma or chronic obstructive lung diseases. The purpose of this study is to determine if the use of inhaled corticosteroids is associated with suppression of endogenous cortisol production, as seen in patients treated with pharmacologic doses of oral or parenteral steroids.

Clinical Trial Description

The normalcy of the hypothalmic-pituitary-adrenal (HPA) axis of enrolled subjects will be assessed by low dose (1mcg) corticotropin (ACTH)stimulation test. Serum cortisol levels will be measured before , 30 minutes and 60 minutes after 1 mcg ACTH intravenous injection. ;

Study Design

Observational Model: Case-Only, Time Perspective: Prospective

Related Conditions & MeSH terms

Adrenal Insufficiency

Clinical Trial Details

NCT number	NCT00560625
Study type	Observational
Source	HaEmek Medical Center, Israel
Contact
Status	Terminated
Phase	N/A
Start date	May 2007
Completion date	December 2008

View Details

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