Pre-meal Planning and Expected Satiety

Adiposity Clinical Trial

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT02427152
• Other study ID #: Satt
• Status: Recruiting
• Phase: N/A
• First received: March 18, 2015
• Last updated: May 29, 2017
• Start date: March 2015
• Est. completion date: December 2017

Study information

• Verified date: May 2017
• Source: University Hospital Tuebingen
• Contact: Hege
• Email: maike.hege[@]med.uni-tuebingen.de
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Obesity is considered to be caused by an imbalance between energy expenditure and energy intake. A major determinant of our daily energy intake is the size of the meals that we consume. It has been suggested that decisions about portion sizes are often made in advance, before a meal begins. This pre-meal planning is considered to especially depend on the estimated 'expected satiety' and 'expected satiation' of different foods. Further, also factors like weight concern and palatability of the food might have their influence on meal size selection. In general, it is not clear how these factors are integrated during pre-meal planning and which brain networks are involved in these decisions/this process. Thus, the investigators plan to study pre-meal planning in healthy, normal-weight and overweight/obese individuals with functional magnetic resonance imaging under different cognitive instructions including pleasure, expected satiety and self-control in terms of health consequences. The investigators will explore the neural networks involved in pre-meal planning and expect them to be modulated by the before mentioned factors. Further, the investigators plan to explore gender differences and expect that female subjects will select smaller portion sizes especially in the self-control condition as they are often more concerned about their weight/health. Finally, the investigators will explore differences between lean and overweight subjects to elucidate factors that might lead to increased meal sizes in overweight subjects.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 60
• Est. completion date: December 2017
• Est. primary completion date: December 2017
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years to 35 Years

Eligibility

Inclusion Criteria:

• body mass index: 18-25 kg/m²; 25-35 kg/m²,

• right-handed,

• age: 18-35 years.

Exclusion Criteria:

• functional magnetic resonance imaging contraindications,

• claustrophobia,

• self-reported eating disorders,

• vegan or vegetarian diet, food allergies,

• intake of antidepressants,

• metabolic disorders.

Related Conditions & MeSH terms

• Adiposity

Locations

Country	Name	City	State
Germany	University Clinic of Tuebingen, fMEG Center	Tuebingen

Sponsors (1)

Lead Sponsor	Collaborator
University Hospital Tuebingen

Country where clinical trial is conducted

Germany, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Differential brain functions in reward, decision making and inhibitory control networks (brain functions will be measured by blood oxygen level dependent effects)	brain functions will be measured by blood oxygen level dependent effects	day 0
Secondary	Differential behavioral measures of portion size selection		day 0