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Adhesive Small Bowel Obstruction clinical trials

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NCT ID: NCT06182319 Recruiting - Clinical trials for Adhesive Small Bowel Obstruction

Optimizing Treatment of Adhesive Small Bowel Obstruction

Start date: January 1, 2024
Phase: Phase 3
Study type: Interventional

Small bowel obstruction (SBO) is one of the most common causes of serious gastrointestinal disease in the US. Adhesion-related SBO (aSBO) is usually treated by the placement of a nasogastric tube (NGT) to decompress the stomach, administration of intravenous (IV) fluids and observation by a surgical team. The purpose of this feasibility study is to determine the potential for implementation of treatment protocols for aSBO and determine the feasibility of randomizing patients with aSBO to receive or not receive NGTs or water-soluble contrast (WSC). The investigators will also determine the ability to measure HRQOL as a main outcome for the treatment of aSBO. The studies outlined in this research program intend to address gaps in knowledge about how to determine who benefits from NGT placement, who can be managed without them, how to objectively determine when a bowel obstruction has resolved, how to reintroduce feeding to patients with aSBO, what criteria should be used for hospital discharge and what role cathartics such as WSC contrast have in the management of aSBO. This feasibility study will enroll a limited number of patients (n=40) who will be followed for up to 30 days.

NCT ID: NCT04318821 Recruiting - Clinical trials for Adhesive Small Bowel Obstruction

Effect of Laser Acupuncture on Adhesive Small Bowel Obstruction

Start date: March 1, 2020
Phase: N/A
Study type: Interventional

Adhesive small bowel obstruction (ASBO) is one of the most common complications and is a major cause of admission after intra-abdominal surgery. To date, the ideal management of ASBO remains controversial. The aim of this protocol designed as a double-blind randomized controlled trial is to investigate the efficacy of laser acupuncture (LA) therapy in patients with ASBO.

NCT ID: NCT03602352 Completed - Clinical trials for Adhesive Small Bowel Obstruction

A Study of the Cost for Patients Operated for Adhesive Obstruction (SBO) During a Five-year Period

Start date: January 1, 2015
Phase:
Study type: Observational

A cohort study of the cost for patients operated for adhesive small bowel obstruction (SBO) during a five-year period

NCT ID: NCT03534596 Completed - Clinical trials for Adhesive Small Bowel Obstruction

Surgery for Adhesive Small Bowel Obstruction in a Defined Population: a Cohort Study

Start date: January 1, 2015
Phase:
Study type: Observational

A cohort study of patients operated for adhesive small bowel obstruction (SBO) during a five-year period

NCT ID: NCT01867528 Active, not recruiting - Clinical trials for Adhesive Small Bowel Obstruction

Comparison of Laparoscopic Surgery Versus Open Surgery in the Treatment of Adhesive Small Bowel Obstruction

Start date: July 2013
Phase: N/A
Study type: Interventional

Small bowel obstruction is a common reason for surgical admission. Most common reason for small bowel obstruction is adhesions, which account up to 70-80 % of small bowel obstructions. Large proportion of adhesive small bowel obstructions may be treated nonoperatively, but up to 50-60% may need surgical intervention. Current golden standard for surgical intervention is open adhesiolysis. Recently, retrospective studies have provided encouraging results of laparoscopic adhesiolysis for small bowel obstructions. However, no prospective randomized trials have been carried out and retrospective series carries a high risk for patient selection and bias. Although in general laparoscopy has been associated with shortened hospital stay, less pain and reduced mortality, laparoscopic adhesiolysis for small bowel obstruction has been reported to cause iatrogenic small bowel lesions up to 7% of patients. Aim of the study is to compare open adhesiolysis to laparoscopic adhesiolysis. The investigators hypothesis is that laparoscopic adhesiolysis is safe, will shorten the hospital stay, and reduce mortality compared to open approach.