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Adhesive Capsulitis clinical trials

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NCT ID: NCT02001740 Completed - Adhesive Capsulitis Clinical Trials

An RCT in Treatment of Adhesive Capsulitis Arthrographic Joint Distention With Local Anesthetic Alone

Start date: December 2012
Phase: Phase 4
Study type: Interventional

Frozen shoulder or adhesive capsulitis is a common cause of shoulder pain, estimated to affect 25% of the general population. Many forms of treatment have been advocated for frozen shoulder including physiotherapy, injection with steroid, distension arthrogram with steroid, manipulation under anesthetic and arthroscopic releases. There is no general agreement in favour of one form of treatment, and the response to a particular treatment varies in different series. A few randomized controlled trials appear in the literature. Most of these showed improvements with steroid use, but the results were not always statistically significant. One randomized control trial reported superior results in favor of arthrographic joint distension with steroid compared to a saline placebo. To our knowledge there have been no other similar randomized trials to support these results. The objective of this study is to determine if arthrographic distension of the shoulder joint with steriods is an effective treatment modality for adhesive capsulitis as compared to injection with local anesthetic and contrast alone. The study design is a placebo-controlled, double blind clinical trial where participants will undergo distension arthrogram of the shoulder and be randomized to receive either Triamcinalone (steroid), lidocaine and contrast or injection with lidocaine and contrast alone.

NCT ID: NCT01817348 Completed - Adhesive Capsulitis Clinical Trials

Effect of Combined Intra-articular Injection of Lidocaine Plus Physiotherapy in Treatment of Frozen Shoulder

Start date: January 2013
Phase: N/A
Study type: Interventional

1. Therapeutic exercise, especially stretch exercise and joint mobilization, remain the mainstay of conservative treatment of frozen shoulder. 1. Nevertheless, shoulder pain during the physiotherapy reduces the treatment effect. 2. Manipulation or arthroscopic release under general anesthesia may avoid pain during the intervention; however, increased risk of humeral shaft fracture and failure of release of pathological tissue were reported. 2. We consider intra-articular injection is a compromized way, from a practical point of veiw, to reduce the pain during physiotherapy. 3. We hypothesize that, intra-articular injection with lidocaine before joint mobilization and stretch exercise, can make the patient pain-free during physiotherapy, and the effect of combined therapy is superior to physiotherapy alone in the treatment of frozen shoulder.

NCT ID: NCT01483963 Completed - Adhesive Capsulitis Clinical Trials

AA4500 for the Treatment of Adhesive Capsulitis of the Shoulder

Start date: November 2011
Phase: Phase 2
Study type: Interventional

The objectives of this study are to assess the safety, effectiveness, and immunogenicity of AA4500 in the treatment of adhesive capsulitis.

NCT ID: NCT01458691 Completed - Adhesive Capsulitis Clinical Trials

Intra-articular Injection of Allogeneic Platelet Rich Plasma (PRP) for Adhesive Capsulitis

Start date: September 2013
Phase: N/A
Study type: Interventional

The purpose of this study is to compare the efficacy of intra-articular allogenic Platelet Rich Plasma injection and steroid injection in the treatment of adhesive capsulitis of the shoulder.

NCT ID: NCT01306708 Completed - Adhesive Capsulitis Clinical Trials

Amitriptyline Regarding Nimesulide in Acute Idiopathic Adhesive Capsulitis

Start date: February 2011
Phase: Phase 2
Study type: Interventional

The adhesive capsulitis is a disease of the shoulder characterized by pain and limitation of movement amplitude. It is defined as for etiology, having discordant theories that related it to an inflammatory condition or to an algoneurodystrophy process. There is not yet a consensus about the best option of treatment. The non-steroidal anti-inflammatories have analgesic and anti-inflammatory activity, where the mechanism of action is the inhibition of prostaglandin synthesis. The antidepressants have been increasingly used in the control of chronic pain and the major action mechanism to have the analgesic effect seems to be based on inhibition of neurotransmitters reuptake noradrenaline and/or serotonin) in nerve cell endings. Literature studies associate the practice of the nerve suprascapular blockade with anaesthetics to good results of clinical improvement of the pain, however, so far, no clinical studies comparing the efficacy of the non-steroidal antiinflammatories or tricyclic antidepressants to nervous blockage were registered in the acute treatment of adhesive capsulitis.

NCT ID: NCT01144533 Completed - Adhesive Capsulitis Clinical Trials

Comparative Analysis of Intra-articular Injection of Steroid and/or Sodium Hyaluronate in Adhesive Capsulitis

Start date: June 2010
Phase: N/A
Study type: Interventional

The purpose of this study is to compare the efficacy of intra-articular steroid injection, sodium hyaluronate injection, a combination of the two, and placebo in the treatment of adhesive capsulitis of the shoulder.

NCT ID: NCT01087229 Completed - Adhesive Capsulitis Clinical Trials

Effectiveness of an Oxygen-nitrous Oxide Mixture During Physical Therapy for Frozen Shoulder

MEOPA
Start date: March 2010
Phase: Phase 4
Study type: Interventional

The purpose of this study is to determine whether or not the use of an equimolar mixture of oxygen and nitrous oxide during the physical therapy for patients suffering from frozen shoulder (adhesive shoulder capsulitis) results in a gain in shoulder amplitude (Constant Score) and less pain as compared to patients undergoing physical therapy without this treatment.

NCT ID: NCT00992927 Completed - Adhesive Capsulitis Clinical Trials

Should the Joint Capsule of the Painful Stiff Shoulder be Ruptured During Intra-articular Hydraulic Distension?

Start date: March 2008
Phase: N/A
Study type: Interventional

The purpose of the study is to compare the efficacy of intra-articular hydraulic distension (IHD) for the treatment of painful stiff shoulders between capsule-rupturing and capsule-preserving IHDs.

NCT ID: NCT00840229 Completed - Adhesive Capsulitis Clinical Trials

Rotator Interval and Intra-articular Corticosteroid Injection for Frozen Shoulder

Start date: February 2009
Phase: N/A
Study type: Interventional

The purpose of this study is to compare ultrasound guided capsular corticosteroid injection into the rotator interval/anterior capsule and the GH joint with ultrasound guided corticosteroid injection into the GH joint only. Both methods will be compared with placebo injections. Primary outcome measure: pain reduction at week 6 Secondary outcome measures: improvement of function (SPADI, Life quality, ROM). 0-hypothesis: no difference between the methods. The investigators want to find out if the clinical effect of the combined capsular and intra-articular injections are better than placebo and better that intra-articular injections

NCT ID: NCT00761943 Completed - Adhesive Capsulitis Clinical Trials

Correlating Clinical Disease State With Color Doppler Ultrasound

Start date: December 2006
Phase: N/A
Study type: Observational

We are trying to see if ultrasound is a good tool for looking at the changes that happen on the inside of the shoulder due frozen shoulder.