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Clinical Trial Summary

Autism Spectrum Disorder (ASD) is often accompanied by a variety of other symptoms, such as bipolar disorder, Attention Deficit Hyperactivity Disorder (ADHD), Social Anxiety Disorder (SAD), Avoidant Personality Disorder (AvPD), Obsessive Compulsive Disorder (OCD), etc. The behavioral and social complications often marginalize the population, impact on life satisfaction, undermined societal values that impact on economic and financial fairness, and so forth. Furthermore, persons with ASD are neurodiverse from standardized pharmacological and clinical cares, and are interpreted disadvantaged in the context of neurotypical treatments. The research protocol aims to differentiate the neuropharmacological implications of ASD from its behavioral and social implications. Such a differentiation is beneficial to the quality of care for neurodiverse population, both in terms of precision treatment in medical settings, and in terms of psychotherapeutic treatment efficacy in the interpretation of behavioral and social traits. The study protocol continues from the adverse event of the participant in NCT05711810 trial, after the positive immunological results in the NCT05839236 trial. The intervention medicine continues from Sertraline adjusted on the choice of Selective Serotonin Reuptake Inhibitor (SSRI) in the previous two trials for complex post-traumatic stress disorder (CPTSD) of the participant, and its combined used with Duloxetine in the choice of Selective Norephedrine Reuptake Inhibitor (SNRI) for norephedrine regulations. The hypothesized target is on the discrete psychiatric intervention centered approach to ASD treatment care. In the PRC where the study is being carried out, amphetamine class medicines are strictly prohibited and defined as illegal substances, regardless of their only proven effect for ASD patient care. Contributed by the sociostructural elements and necessities, black market amphetamine and ketamine have not only emerged in the regime for decades, but also have become a lucrative business. Their recreational uses are also sometimes accompanied by real necessities and needs; black markets cater to the needs but guidance on the usages is based on word-of-mouth stories without professional medical assistances. There is one case the Principal Investigator (PI) collected, that one person, possibly under depression contributed by PTSD, took relatively high dosage of amphetamine and went into a state of psychosis with overwhelming persecution mania. The study protocol, Psychiatric Orders in Psychoanalytic Treatment of ASD, is therefore designed for an evidence-based approach in treating complex psychiatric disorders with psychoanalytic guidance.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms

  • ADHD - Combined Type
  • Adjustment Disorders
  • Agoraphobia
  • Agoraphobia With Panic Attacks
  • Anxiety Disorders
  • Autism Spectrum Disorder
  • Autism Spectrum Disorder High-Functioning
  • Avoidant Personality Disorder
  • Borderline Personality Disorder
  • Depression
  • Depression and Suicide
  • Depression Anxiety Disorder
  • Depression, Anxiety
  • Depression, Reactive
  • Depression, Unipolar
  • Depression; Psychoneurotic
  • Depressive Disorder
  • Grief
  • OCD
  • Panic Disorder
  • Personality Disorders
  • Phobia, Social
  • PTSD
  • Social Anxiety Disorder
  • Suicide

NCT number NCT05930912
Study type Observational
Source Pachankis, Yang I., M.D.
Contact
Status Active, not recruiting
Phase
Start date June 1, 2023
Completion date December 1, 2023

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