Primary Immune Deficiency Disorder Clinical Trial
Official title:
A Pilot Study in the Treatment of Refractory Adenovirus (ADV) Infection With Related Donor ADV Cytotoxic T-Lymphocytes (ADV-CTLs)in Children, Adolescents and Young Adult Recipients
Related donor Adenovirus (ADV) specific cytotoxic T cells (CTLs) manufactured with the Miltenyi CliniMACS Prodigy Cytokine Capture System will be administered intravenously in in children, adolescents and young adults with refractory ADV infection post Allogeneic Hematopoietic Stem Cell Transplantation (AlloHSCT), with primary immunodeficiencies (PID) or post solid organ transplant. Funding Source: FDA OOPD
n/a
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT03939533 -
Study to Monitor Subcutaneous Human Immunoglobulin Administered at Modified Dosing Regimens in Patients With Primary Immunodeficiency Diseases
|
Phase 3 | |
Recruiting |
NCT03266640 -
Virus Specific Cytotoxic T-Lymphocytes (CTLs) for Refractory Cytomegalovirus (CMV)
|
Phase 2 | |
Completed |
NCT01859754 -
Octagam 5% Versus Comparator Post Marketing Trial
|
||
Recruiting |
NCT03148028 -
Immunological Characteristics of Patients With PID and IBD
|
N/A | |
Active, not recruiting |
NCT04354818 -
Coronavirus (COVID-19) Outcomes Registries in Immunocompromised Individuals Australia (CORIA)
|
||
Completed |
NCT03988426 -
Study to Evaluate the Efficacy, Tolerability and Safety of Octanorm in Patients With Primary Immunodeficiency Diseases
|
Phase 3 | |
Completed |
NCT01888484 -
Study of Octanorm Subcutaneous IG in Patients With PID
|
Phase 3 | |
Completed |
NCT01131858 -
Study of Vitamin D3 Substitution to Patients With Primary Immunodeficiency
|
Phase 1/Phase 2 | |
Completed |
NCT03211689 -
The Impact of Exercise on Stress, Fatigue, and Quality of Life in Individuals With Primary Immunodeficiency Disease
|
N/A | |
Terminated |
NCT01883921 -
Gamma Globulin Observations and Outcomes Database for Patients With Primary Immunodeficiency Disease (GOOD-SHEPARD-PI)
|
||
Recruiting |
NCT03266653 -
EBV-specific Cytotoxic T-lymphocytes (CTLs) for Refractory EBV Infection
|
Phase 2 | |
Completed |
NCT02327351 -
TCR Alpha/Beta Depletion for HSCT From Haploidentical and Unrelated Donors in the Treatment of PID
|
Phase 2/Phase 3 | |
Completed |
NCT03618147 -
Primary Immunodeficiency in Kuwait
|
||
Recruiting |
NCT04197596 -
Treatment of Refractory BK Infections With Related Donor BK Specific Cytotoxic T-cells (CTLs)
|
Phase 1/Phase 2 | |
Recruiting |
NCT03422614 -
Pathophysiology of Inborn Immunodeficiencies
|
N/A | |
Completed |
NCT02888535 -
Intensive Care Unit and Secondary and Primary Immune Deficiency
|
||
Recruiting |
NCT04232085 -
Reduced Intensity BMT for Immune Dysregulatory and Bone Marrow Failure Syndromes Using Post-Transplant Cyclophosphamide
|
Phase 2 | |
Active, not recruiting |
NCT03037359 -
A Study About Low Blood Pressure in Patients With Primary Immunodeficiency Disease Treated With Immune Globulin Products
|
||
Completed |
NCT03069079 -
Investigation of Dental Health in Children With Neutrophil Defects: A Clinical Study
|
N/A | |
Recruiting |
NCT03414528 -
Identification of New Inborn Errors of Immunity
|
N/A |