Dienogest for Treatment of Adenomyotic Uteri

Status Completed

Clinical Trial Summary

Adenomyosis is a common disease in women aged 40-50 years. It associates with dysmenorrhea and menorrhagia. Hysterectomy was considered the main treatment that could definitively cure this disease. Other treatment options are increasingly offered, including hormonal suppression with gonadotropin-releasing hormone agonists or danazol and endometrial ablation. However, deep adenomyosis responds weakly to the above treatment options, which are commonly not considered for long-term management because of the associated side effects.

Dienogest is a progestin medication which is used in birth control pills and in the treatment of endometriosis and adenomyosis. Low-dose combined oral contraceptive (COC) pills have been widely used as the primary treatment for menorrhagia. COCs can also be used to induce endometrial atrophy and to decrease endometrial prostaglandin production, which can consequently improve menorrhagia and dysmenorrhea that are associated with adenomyosis

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Adenomyosis

Clinical Trial Details

NCT number	NCT03890042
Study type	Interventional
Source	Assiut University
Contact
Status	Completed
Phase	N/A
Start date	March 1, 2019
Completion date	August 1, 2020

View Details

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