Adenoma Colon Polyp Clinical Trial
Official title:
LCI (Linked Color Imaging) for Adenoma Detection in the Right Colon
Although colonoscopy with polypectomy can prevent up to 80% of colorectal cancers, a
significant adenoma miss rate still exists, particularly in the right colon. Optimizing the
detection of adenomas and sessile serrated lesions in the right colon is crucial to increase
the effectiveness of colonoscopy in colorectal cancer prevention.
Last generation Fuji videocolonscopes incorporates the Linked Color Imaging (LCI), a recently
developed technology that differentiates the red colour spectrum more effectively than White
Light imaging thanks to its optimal pre-process composition of light spectrum and advanced
signal processing. The increased colour contrast results in more accurate delineation of
abnormal inflammatory or neoplastic findings of colonic mucosa. Preliminary data suggest that
LCI may be improve the detection of neoplastic lesion of colon.
The investigators performe a tandem prospective study to compare the right colon adenoma miss
rates of LCI colonoscopy with those of conventional white light colonoscopy.
Therefore participants scheduled for colonoscopy for the assessment of symptoms or for
colorectal cancer screening/surveillance receive the examination of the right colon twice, in
a back to back fashion, with standard white light (WL) and with LCI. Patients are randomly
assigned (1:1), via computer-generated randomisation with block size of 20, to which
procedure is done first. The endoscopist are masked to group allocation until immediately
before the cecum is reached. Examinations are performed with Fuji videocolonscopes series 700
(EC-760R, EC-760ZP).
n/a
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Not yet recruiting |
NCT06406062 -
Artificial Intelligence-assisted System in Colonoscopy
|
||
| Completed |
NCT03775811 -
In Vivo Computer-aided Prediction of Polyp Histology on White Light Colonoscopy
|