Concordance of Imaging and Pathology Diagnosis of Extranodal Tumour Deposits — COMET  

Adenocarcinoma of the Rectum Clinical Trial

Official title: Concordance of Imaging and Pathology Diagnosis of Extranodal Tumour Deposits

Status Recruiting

Clinical Trial Summary

Any patient with a suspected primary adenocarcinoma of the colon, sigmoid or rectum undergoing surgery are eligible. The date of surgery must be known prior to registration. This trial aims to determine if image mapping techniques can improve the concordance between imaging and pathology detection of tumour deposits. Lymph nodes and tumour deposits will be identified on pre-operative scans and mapped by radiologists then shared with pathologists prior to processing the resected specimen. Patients will be managed at their local hospital with standard follow-up. Patients will be followed up for 5 years.

Clinical Trial Description

A prospective interventional multi-centre study, COMET aims to prove the accuracy of imaging diagnosis of extranodal tumour deposits (TD) and their adverse effect on prognosis of colorectal cancers. The proposed intervention will be additional radiological and pathological assessment and the reporting of supplementary diagnostic information which would not otherwise have been available. This may affect treatment according to local MDT protocols and also affect the provision of prognostic information to patients in subsequent discussions. ;

Related Conditions & MeSH terms

• Adenocarcinoma of the Rectum

• NCT number: NCT03303547
• Study type: Interventional
• Source: Imperial College London
• Contact: Caroline Martin
• Phone: +44 (0) 7749 655 817
• Email: c.martin1@imperial.ac.uk
• Status: Recruiting
• Phase: N/A
• Start date: October 16, 2017
• Completion date: December 2029