The Effectiveness of tDCS on Internet Game Addiction

Addiction Clinical Trial

Official title:

Randomized Double-blind Clinical Trial to Evaluate the Effectiveness of Transcranial Direct Current Stimulation (tDCS) on Internet Game Addiction

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03347643
• Other study ID #: 30-2017-10
• Status: Completed
• Phase: Phase 2
• Start date: September 22, 2017
• Est. completion date: October 8, 2019

Study information

• Verified date: March 2020
• Source: Seoul National University Hospital
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

In this study, the investigators aimed to investigate the effect of transcranial direct current stimulation (tDCS) on clinical status of Internet game addiction. The clinical status of Internet game addiction includes severity of addiction symptom, subjective craving for gaming, response inhibition and cue reactivity. The investigators hypothesized that real stimulation with tDCS on the dorsolateral prefrontal cortex will have higher effectiveness on severity of addiction symptom, subjective craving for gaming, response inhibition and cue reactivity rather than sham stimulation with tDCS.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 31
• Est. completion date: October 8, 2019
• Est. primary completion date: September 1, 2019
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 50 Years

Eligibility

Inclusion Criteria:

• Diagnosis of Internet gaming disorder based on diagnostic criteria of Diagnostic and Statistical Manual of Mental Disorders (DSM)-5.

Exclusion Criteria:

• History of seizure

• History of significant head injury

• Mental retardation

• Schizophrenia

• History of stroke

Related Conditions & MeSH terms

• Addiction
• Behavior, Addictive
• Internet Gaming Disorder

Intervention

Device:
• tDCS with real stimulation
tDCS is a non-invasive brain stimulation. Real stimulation includes 2mA current for 20 minutes per session. Two sessions a day for 5 consecutive days (Total: 10 sessions) will be applied.
• tDCS with sham stimulation
Sham stimulation includes 0mA current for 20 minutes per session. Two sessions a day for 5 consecutive days (Total: 10 sessions) will be applied.

Locations

Country	Name	City	State
Korea, Republic of	SMG-SNU Boramae Medical Center	Seoul

Sponsors (3)

Lead Sponsor	Collaborator
Seoul National University Hospital	National Research Foundation of Korea, SMG-SNU Boramae Medical Center

Country where clinical trial is conducted

Korea, Republic of, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Young Internet Addiction Test (Y-IAT)	The Y-IAT is rated on a five-point scale. Total scores for all 20 items range from 20 to 100.	baseline
Primary	Young Internet Addiction Test (Y-IAT)	The Y-IAT is rated on a five-point scale. Total scores for all 20 items range from 20 to 100.	1 week
Primary	Young Internet Addiction Test (Y-IAT)	The Y-IAT is rated on a five-point scale. Total scores for all 20 items range from 20 to 100.	5 week
Primary	Young Internet Addiction Test (Y-IAT)	The Y-IAT is rated on a five-point scale. Total scores for all 20 items range from 20 to 100.	25 week
Secondary	Direction error and successful stop ratio in the Stop signal task	The stop signal task is a neurocognitive task for assessing response inhibition.	baseline, 5 weeks, 25 weeks
Secondary	Barratt impulsiveness scale-11	Barratt impulsiveness scale-11 is a self-report questionnaire consisting of 30 items. Each question has a 4-point scale ranging from 1 (rarely/never) to 4 (almost always/always). This scale scores three subscales: attentional impulsiveness, motor impulsiveness, and nonplanning impulsiveness. The total score ranges from 30 to 120 and higher scores indicate greater impulsivity.	baseline, 5 weeks, 25 weeks
Secondary	Anti-saccade error rate in the attentional bias task	The attentional bias task is measured by anti-saccade task using eye-tracking analysis for assessing attentional bias on Internet gaming stimuli.	baseline, 5 weeks, 25 weeks
Secondary	Late positive potential in the cue reactivity event-related potential	Event-related potential measures with cue reactivity task	baseline, 5 weeks, 25 weeks
Secondary	Visual analogue scale	Subjective craving for Internet gaming ranging from 0 to 10. Higher score represents higher craving for gaming.	baseline, 1 week, 5 weeks, 25 weeks