Clinical Trials Logo
  1. Home
  2. AD
  3. NCT03932916

Safety and Pharmacokinetic of Donepezil Pamoate in Healthy Subjects

AD Clinical Trial

Official title:
Evaluation of Safety and Pharmacokinetic Profiles of a Single-dose HHT201 in Healthy Subjects

Clinical Trial Summary

The objective of this study is to evaluate the safety and pharmacokinetic profiles of HHT201 in healthy subjects.

Clinical Trial Description

The study aims to evaluate the safety, pharmacokinetics and to determine the potential dose limiting toxicity of HHT201 in healthy subjects between the ages of 20-59, 6 in 17mg dose group and 20 in 34mg dose group. Another 12 subjects will be administered a tablet of 5mg Donepezil Hydrochloride to get the PK profile of Donepezil as reference. Eligible subjects will be accepted into the protocol after review and providing voluntary written informed consent forms and completion of a comprehensive medical, physical examination, and routine laboratory assessment. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03932916
Study type Interventional
Source Shanghai Synergy Pharmaceutical Sciences Co., Ltd.
Contact
Status Completed
Phase Phase 1
Start date July 2, 2019
Completion date September 11, 2020
View Details
See also
  Status Clinical Trial Phase
Not yet recruiting NCT04520308 - An Open-label, Single-arm Longitudinal Study With Dupilumab for Patients With Atopic Dermatitis Phase 4
Recruiting NCT06155201 - Development and Application of Intelligent Diagnosis and Treatment Norms for Children and Adolescents With Mental Disorders N/A
Recruiting NCT06335836 - The Effects of Social Isolation and Social Interaction on the Risk of Dementia Progression and Brain Function in SCD (Subjective Cognitive Decline, SCD)
Active, not recruiting NCT02380573 - Effects of Methylene Blue in Healthy Aging, Mild Cognitive Impairment and Alzheimer's Disease Phase 2
Terminated NCT01733355 - A Phase 0, Open Label, Multi-center Exploratory and Safety Study of [F-18]T807 Phase 0
Completed NCT01190904 - Hormones and Sexual Function Predict Outcomes in Revascularized Men With Diabetes N/A
Recruiting NCT05372458 - The Mechanism Study of Diabetic Pancreatic Amyloid Deposition on Cognitive Dysfunction in Alzheimer's Disease
Enrolling by invitation NCT06245031 - Extension to a Pivotal Study of Sensory Stimulation in Alzheimer's Disease (OLE Hope Study, CA-0015) N/A
Active, not recruiting NCT05984784 - A Study to Evaluate the Safety, Pharmacokinetics, and Efficacy of IMG-007 in Adults With Atopic Dermatitis (AD) Phase 1/Phase 2
Completed NCT02273895 - The Use of EEG in Alzheimer's Disease, With and Without Scopolamine - A Pilot Study N/A