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NCT01152424 Clinical Trial

Usefulness of Exhaled NO in the Differential Diagnosis Acute Eosinophilic Pneumonia and Bacterial Pneumonia

Acute Clinical Trial

Official title:
Usefulness of Exhaled NO in the Differential Diagnosis Acute Eosinophilic Pneumonia and Community Acquired Pneumonia

Clinical Trial Details — Status: Active, not recruiting

Administrative data
NCT number NCT01152424
Other study ID # FeNO in AEP
Secondary ID
Status Active, not recruiting
Phase N/A
First received June 24, 2010
Last updated June 7, 2011
Start date July 2010
Est. completion date December 2011

Study information
Verified date June 2011
Source Seoul National University Bundang Hospital
Contact n/a
Is FDA regulated No
Health authority South Korea: Ministry of National DefenseSouth Korea: Korea Food and Drug Administration (KFDA)
Study type Observational

Clinical Trial Summary

Acute eosinophilic pneumonia (AEP) is diagnosed by cell count analysis of bronchoalveolar lavage fluid. However, the performance of bronchoscopy is not easy for patients with AEP, because they usually have hypoxia. Exhaled nitric oxide (FeNO) is usually elevated in the patients with eosinophilic inflammation such as asthma, but there is no previous studies FeNO in the patients with AEP. Investigators hypothesized that FeNO elevated significantly in patients with AEP, and FeNO can be used as non-invasive diagnostic method in patients who are clinically suspected with AEP, especially when the performance of bronchoscopy is difficult.

Recruitment information / eligibility
Status Active, not recruiting
Enrollment 50
Est. completion date December 2011
Est. primary completion date April 2011
Accepts healthy volunteers No
Gender Both
Age group N/A and older
Eligibility Inclusion Criteria:

- All patients who visited the study hospital with bilateral pneumonic infiltration.

Exclusion Criteria:

- Patients who do not agree with our study protocol

Study Design

Observational Model: Case Control, Time Perspective: Prospective

Related Conditions & MeSH terms

Locations
Country Name City State
Korea, Republic of Armed Forces Capital Hospital Seongnam Gyeongi

Sponsors (1)
Lead Sponsor Collaborator
Seoul National University Bundang Hospital

Country where clinical trial is conducted

Korea, Republic of, 

Outcome
Type Measure Description Time frame Safety issue
Primary The difference of FeNO in AEP and Community Acquired Pneumonia Six months No
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