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Clinical Trial Details — Status: Recruiting

Administrative data

NCT number NCT05186636
Other study ID # Pro00112499
Secondary ID
Status Recruiting
Phase
First received
Last updated
Start date January 12, 2023
Est. completion date June 30, 2025

Study information

Verified date October 2023
Source University of Alberta
Contact Dawn Opgenorth, RN
Phone 780 492-4698
Email dawno@ualberta.ca
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

Implementation of an evidence-based and best practices acute RRT pathway aiming to decrease acute RRT program and healthcare systems costs while improving important patient-reported outcomes.


Description:

Providing acute dialysis to critically ill patients in ICU settings is resource and cost intensive. The daily costs of acute dialysis can range from $528/day for intermittent hemodialysis to $865/day for continuous renal replacement therapy. Providing acute dialysis in ICU settings requires a specialized team of nurses, educators, physicians and stakeholders to ensure its safe and effective prescription and delivery. Acute dialysis is typically delivered to some of the most acutely ill patients admitted to the ICU to support organ function and sustain life. At present, there is not a standardized approach to the prescription and delivery of acute dialysis therapy in ICUs across Alberta. The DIALYZING WISELY program will implement a standardized approach to the delivery of best practices for acute dialysis therapy to all patients who receive treatment across ICUs in Alberta.


Recruitment information / eligibility

Status Recruiting
Enrollment 4500
Est. completion date June 30, 2025
Est. primary completion date December 31, 2024
Accepts healthy volunteers No
Gender All
Age group N/A and older
Eligibility Inclusion Criteria: Patient in one of 15 adult and 3 pediatric intensive care units in Alberta Receive acute RRT as part of their usual clinical care during the intervention period Exclusion Criteria: - none

Study Design


Related Conditions & MeSH terms


Intervention

Other:
KPI reports
Quarterly
Prescriber reports
Individualized prescriber reports for acute RRT initiation patterns along with targeted education to ensure that align with best evidence-based practices

Locations

Country Name City State
Canada Foothills Medical Centre Calgary Alberta
Canada Peter Lougheed Centre Calgary Alberta
Canada University of Alberta Hospital Edmonton Alberta
Canada Red Deer Regional Hospital Centre Red Deer Alberta
Canada Sturgeon Community Hospital St. Albert Alberta

Sponsors (2)

Lead Sponsor Collaborator
University of Alberta Alberta Innovates Health Solutions

Country where clinical trial is conducted

Canada, 

Outcome

Type Measure Description Time frame Safety issue
Primary Key performance indicators (KPI) Changes in acute KPIs Throughout intervention period up to 3 years
Primary Health system costs Acute RRT and healthcare systems costs 3 years
Secondary Length of renal replacement therapy Length of time patient receives RRT during their ICU stay 3 years
Secondary ICU and hospital lengths of stay Number of days patient spends in the ICU and hospital 3 years
Secondary ICU and 90 day mortality number of patients who die before ICU discharge or within 90 days of ICU stay 3 years
Secondary Rates of RRT dependence at 90 days number of patients who are receiving RRT at 90 days after ICU stay 3 years
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