Early Renal Replacement Therapy and the Outcome of Acute Kidney Injury

Acute Renal Failure Clinical Trial

— EarlyRRT  

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT01819038
• Other study ID #: chula
• Status: Completed
• Phase: N/A
• First received: March 18, 2013
• Last updated: January 26, 2016
• Start date: January 2013
• Est. completion date: December 2015

Study information

• Verified date: December 2015
• Source: Chulalongkorn University
• Contact: n/a
• Is FDA regulated: No
• Health authority: Thailand: Ethical Committee
• Study type: Interventional

Clinical Trial Summary

This research project is a prospective study to compare mortality between early renal replacement therapy (RRT) and late renal replacement therapy by using plasma neutrophil gelatinase associated lipocalin (pNGAL) as a tool in decision- making.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 60
• Est. completion date: December 2015
• Est. primary completion date: December 2015
• Accepts healthy volunteers: No
• Gender: Both
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• The patient must have given his/her informed and signed consent

• patients with acute kidney injury in the intensive care ward.

Exclusion Criteria:

• The patient refuses to sign the consent

• The patient is pregnant, parturient, or breastfeeding

• End stage renal disease

• Chronic renal failure

• previous kidney transplant

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Treatment

Related Conditions & MeSH terms

• Acute Kidney Injury
• Acute Renal Failure

Intervention

Procedure:
• continuous renal replacement therapy

Locations

Country	Name	City	State
Thailand	King Chulalongkorn Memorial Hospital	Bangkok

Sponsors (1)

Lead Sponsor	Collaborator
Chulalongkorn University

Country where clinical trial is conducted

Thailand, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Other	hemodialysis free-days		28 days	Yes
Primary	mortality rate		28 day	Yes
Secondary	ventilator free-days		28 days	Yes