Prevention of Acute Radiation Enteritis With Glutamine

Acute Radiation Enteritis Clinical Trial

Official title: Efficacy of Glutamine in the Prevention of Acute Radiation Enteritis Among Patients Treated With Radiation of Abdomen and Pelvis.

Status Completed

Clinical Trial Summary

Ionizing radiation has cytotoxic effects, and is commonly used as treatment for neoplasm. A common adverse effect of radiation is acute diarrhoea. Glutamine is an aminoacid with antioxidant effects that can protect tissues of damage dued to radiation. The investigators designed a randomized, double-blind trial phase III to study if glutamine prevents acute radiation enteritis.

Clinical Trial Description

n/a

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor), Primary Purpose: Prevention

Related Conditions & MeSH terms

• Acute Radiation Enteritis
• Enteritis

• NCT number: NCT00828399
• Study type: Interventional
• Source: Castilla-León Health Service
• Status: Completed
• Phase: Phase 4
• Start date: January 2009
• Completion date: May 2011