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Acute Pulmonary Embolism clinical trials

View clinical trials related to Acute Pulmonary Embolism.

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NCT ID: NCT05318092 Completed - Pulmonary Embolism Clinical Trials

Evaluating the Safety and Efficacy of the AlphaVac Multipurpose Mechanical Aspiration (MMA) F1885 PE for Treatment of Acute Pulmonary Embolism

APEX-AV
Start date: October 19, 2022
Phase: N/A
Study type: Interventional

To evaluate the safety and effectiveness of percutaneous mechanical aspiration thrombectomy using the AlphaVac Multipurpose Mechanical Aspiration (MMA) F1885 PE in a prospective trial of patients with acute intermediate-risk pulmonary embolism (PE).

NCT ID: NCT04037423 Completed - Clinical trials for Acute Pulmonary Embolism

European Database on Catheter-directed Treatment of Pulmonary Embolism.

EuroPE-CDT
Start date: June 4, 2019
Phase:
Study type: Observational [Patient Registry]

The main goals of EuroPE-CDT is to assess the currently applied catheter-directed treatment (CTD) techniques and strategies in pulmonary embolism (PE) patients and to determine the short term efficacy and safety of this invasive procedure.

NCT ID: NCT03966079 Completed - Pulmonary Embolism Clinical Trials

Thrombolysis Endovascular Treatment of Pulmonary Embolism

STEP
Start date: January 1, 2017
Phase: Phase 3
Study type: Interventional

To assess the efficacy and safety of endovascular thrombolysis of pulmonary embolism with right ventricular dysfunction with single-dose rtPA

NCT ID: NCT03631810 Completed - Clinical trials for Acute Pulmonary Embolism

Contemporary Clinical Management Of Acute Pulmonary Embolism

COPE
Start date: March 15, 2018
Phase:
Study type: Observational [Patient Registry]

Acute pulmonary embolism is a potentially life-threatening disease with short-term mortality ranges from less than 1% to more than 30% during the hospital stay. Recent guidelines recommend to tailor diagnosis hospitalization and acute treatment based on the estimated risk for short-term Death. The assessment of the contemporary clinical management of patients with acute pulmonary embolism across different specialties would be of crucial value.

NCT ID: NCT03108833 Completed - Clinical trials for Acute Pulmonary Embolism

A Trial in Recombinant Human Prourokinase to Treat Acute Pulmonary Embolism

ERUPTE
Start date: June 6, 2017
Phase: Phase 2
Study type: Interventional

This trial is being conducted to assess the efficacy and safety of recombinant Human Prourokinase in the acute pulmonary embolism.

NCT ID: NCT02692586 Completed - Pulmonary Embolism Clinical Trials

FlowTriever Pulmonary Embolectomy Clinical Study

FLARE
Start date: April 2016
Phase: N/A
Study type: Interventional

Evaluate the safety and effectiveness of the FlowTriever System for use in the removal of emboli from the pulmonary arteries in the treatment of acute pulmonary embolism.

NCT ID: NCT01604538 Completed - Clinical trials for Acute Pulmonary Embolism

Italian Pulmonary Embolism Registry - IPER

IPER
Start date: March 2006
Phase: N/A
Study type: Observational

RAZIONALE Pulmonary embolism is a complex disease, with a highly variable clincal presentation. Diagnosis starts with clinical probability assessment mainly based on medical history and rapidly available clinical data. Pulmonary embolism can be managed by emergency department, cardiology, pneumology geriatrics or internal medicine physicians. Thus, initial clinical management can varies based on the attitude of the attending physician. Diagnosis is a crucial point as it can influence short term mortality. OBJECTIVE The registry has 3 main objectives: 1. educational objective, 2. improvement in the knowledge of epidemiology, management and outcome of acute pulmonary embolism in Italy 3. scientific objective

NCT ID: NCT01513759 Completed - Pulmonary Embolism Clinical Trials

Submassive and Massive Pulmonary Embolism Treatment With Ultrasound Accelerated Thrombolysis Therapy

SEATTLE II
Start date: June 7, 2012
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine if the EKOS EkoSonic® Endovascular Device when used in conjunction with recombinant tissue plasminogen activator (t-PA) as a treatment for acute PE will decrease the ratio of right ventricle (RV) to left ventricle (LV) diameter within 48 =/- 6 hours in participants with massive or submassive PE.

NCT ID: NCT01014156 Completed - Clinical trials for Acute Pulmonary Embolism

Epoprostenol in Pulmonary Embolism

Start date: January 2004
Phase: Phase 4
Study type: Interventional

You are admitted to hospital because of pulmonary embolism. You are treated with anticoagulants. The investigators know that, despite this treatment, pulmonary embolism can be a threat especially if heart function is compromized. The investigators investigate a well known study drug (epoprostenol) on top of regular treatment with anticoagulants, to see if heart function can be optimized

NCT ID: NCT00711308 Completed - Clinical trials for Acute Pulmonary Embolism

Tinzaparin in the Treatment of the Acute Pulmonary Embolism

Start date: April 2005
Phase: Phase 4
Study type: Interventional

The purpose of this study is to evaluate the feasibility of the long-term treatment of pulmonary embolism with tinzaparin compared to oral anticoagulants.