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Clinical Trial Details — Status: Recruiting

Administrative data

NCT number NCT06447584
Other study ID # Soh-Med-24-5-2024-09MS
Secondary ID
Status Recruiting
Phase
First received
Last updated
Start date June 1, 2024
Est. completion date June 1, 2025

Study information

Verified date June 2024
Source Sohag University
Contact Asmaa A Saber, resident
Phone 01115205714
Email asmaa_asaad_post@med.sohag.edu.eg
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

Acute poisoning is a major health problem that leads to emergent hospital admission.It has become the main factor that harms children and leads to disability and death of children. Also, it is still a serious issue in developing countries where it represents a common cause of emergency department presentation and admission. Acute poisoning can be divided into two categories (accidental and intentional),accidental poisoning is common in children under five years, whereas intentional poisoning is more common in adolescents, WHO estimated that, in 2016, accidental poisoning caused 106,683 deaths and the loss of 6.3 million years of healthy life. A study in Romania showed that intentional poisoning is the most common cause of poisoning among teenagers. Females are more vulnerable to suicidal or intentional poisoning than males. Medications, alcohol, and substance abuse are common poisoning agents among teenagers , another study at tertiary Indian hospital, pesticides, pharmaceutical drugs, and household products were the most common types of acute poisoning. Pesticides were reported as a cause of intentional and accidental poisoning. In agricultural areas, people were poisoned accidentally by pesticides that may be used for suicidal attempts because of their availability. Pharmaceutical drugs are also used for intentional poisoning due to the availability of street drugs and over-the-counter medications. Accidental poisoning by household products were observed in children and the most common products are hydrocarbon and naphthalene In Egypt acute poisoning represents a significant proportion of emergency visits of children and young people. This labors a burden on healthcare, society and economy and thus, it drain-s resources and multiplies workload . In fact, it is a preventable cause of morbidity and mortality. Children poisoning is a result of multiple risk factors including social, demographic, and industrial factors. Insufficient public awareness, easy accessibility to poison, negligence of caregivers, technological and industrial advances and even the nature of the environment are of the main causes.


Recruitment information / eligibility

Status Recruiting
Enrollment 100
Est. completion date June 1, 2025
Est. primary completion date June 1, 2025
Accepts healthy volunteers
Gender All
Age group 1 Month to 18 Years
Eligibility Inclusion Criteria: - All patients admitted to pediatric emergency and intensive care units with claim or suspected to have acute poisoning aged from 1 month Up to 18 years old. Exclusion Criteria: - Children with chronic poisoning - no clear history or clinical picture of definite toxic poison - incomplete clinical data

Study Design


Related Conditions & MeSH terms


Locations

Country Name City State
Egypt Sohag university Hospital Sohag

Sponsors (1)

Lead Sponsor Collaborator
Sohag University

Country where clinical trial is conducted

Egypt, 

References & Publications (4)

Abdel Baseer KA, Gad EF, Abdel Raheem YF. Clinical profile and outcome of acute organophosphate poisoning in children of Upper Egypt: a cross-sectional study. BMC Pediatr. 2021 Feb 26;21(1):98. doi: 10.1186/s12887-021-02563-w. — View Citation

Ballesteros MF, Williams DD, Mack KA, Simon TR, Sleet DA. The Epidemiology of Unintentional and Violence-Related Injury Morbidity and Mortality among Children and Adolescents in the United States. Int J Environ Res Public Health. 2018 Mar 28;15(4):616. doi: 10.3390/ijerph15040616. — View Citation

Heron M. Deaths: Leading Causes for 2015. Natl Vital Stat Rep. 2017 Nov;66(5):1-76. — View Citation

Jesslin J, Adepu R, Churi S. Assessment of prevalence and mortality incidences due to poisoning in a South Indian tertiary care teaching hospital. Indian J Pharm Sci. 2010 Sep;72(5):587-91. doi: 10.4103/0250-474X.78525. — View Citation

Outcome

Type Measure Description Time frame Safety issue
Primary Recovery Time of acute poisoning Full Recovery with appropriate and timely medical intervention 1 year
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