Prognosis of Elderly Patients With Acute Poisoning.

Acute Poisoning Clinical Trial

Official title:

Evaluation of the Risk Factors Influencing the Prognosis of Elderly Patients With Acute Poisoning.

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT05185570
• Other study ID #: Soh-Med-21-12-01
• Status: Not yet recruiting
• Start date: January 2022
• Est. completion date: October 2022

Study information

• Verified date: December 2021
• Source: Sohag University
• Contact: Abeer H Mohammed
• Phone: 01019585267
• Email: abeer011116[@]med.sohag.edu.eg
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Acute poisoning is a major public health problem all over the world, it causes significant mortality and morbidity. It primarily involves younger populations, with less than 3% of the affected cases being in people aged 60 years or older in most studies. More than half of the intoxication events in the elderly over 65 years old were accidental.

Description:

The elderly are different from younger adults in many aspects. There are age related physiological changes. They have a higher incidence of comorbidities and use of many medications for chronic conditions, both of which make the elderly more susceptible to acute poisoning and its related consequences.

Although the elderly form a relatively small proportion of those admitted to hospital for acute self-poisoning, the poisoning in them is often more serious, complications are more frequent and a fatal outcome is more common.

The presence of multiple physical, social, and psychiatric problems, with possible difficulties in the diagnosis of poisoning make the management of the elderly more complicated than that of younger poisoned patients. There are three main difficulties in diagnosing acute poisoning in the elderly. At first, it may not be easily obvious that the patient has taken an overdose. Secondly, the presence of pre-existing diseases may obscure the clinical picture and finally, the drug may cause physical signs that similar to common problems of old age.

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 20
• Est. completion date: October 2022
• Est. primary completion date: June 2022
• Accepts healthy volunteers: No
• Gender: All
• Age group: 60 Years and older

Eligibility

Inclusion Criteria:

all patients more than 60 years will be included.

Exclusion Criteria:

younger than 60 years.

Related Conditions & MeSH terms

• Acute Poisoning
• Poisoning

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Sohag University

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Change in Acute physiology and chronic health evaluation II score (APACHE II) in cases of elderly patients with acute poisoning.	"Acute Physiology And Chronic Health Evaluation II(APACHE II) " is a severity-of-disease classification system. one of several ICU scoring systems. It is applied within 24 hours of admission of a patient to an intensive care unit (ICU): an integer score from 0 to 71 is computed based on several measurements; higher scores correspond to more severe disease and a higher risk of death.	24 hours after admission to intensive care unit (ICU).
Primary	Change in Poisoning Severity Score (PSS) in cases of elderly patients with acute poisoning.	"Poisoning Severity Score (PSS)" is a standardized scale for grading the severity of poisoning allows qualitative evaluation of. morbidity caused by poisoning, better identification of real risks and comparability of data.	24 hours after admission to intensive care unit (ICU).