A Predictive Model for Recurrent Acute Pancreatitis

Acute Pancreatitis Clinical Trial

Official title:

Construction and Validation of an Early Prediction Nomogram for Recurrent Acute Pancreatitis Based on the MIMIC Database

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT06464887
• Other study ID #: 20200047
• Status: Completed
• Start date: January 1, 2016
• Est. completion date: June 30, 2018

Study information

• Verified date: June 2024
• Source: Yangzhou University
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

The goal of this observational study is to learn about recurrent acute pancreatitis (RAP) .The main questions it aims to answer are:

1. What are the risk factors for RAP?

2. How to predict RAP?

All patients with acute pancreatitis will be given standardized treatment for the condition.

The researchers will compare the RAP group with the non-RAP group to find the risk factors for RAP.

Description:

We retrospectively collected data from the Medical Information Mart for Intensive Care-IV (MIMIC-IV) database and from patients with acute pancreatitis (AP) in the Department of Gastroenterology of Clinical Medical College of Yangzhou University between January 2016 and December 2017, forming the primary and validation cohort, respectively.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 659
• Est. completion date: June 30, 2018
• Est. primary completion date: December 31, 2017
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Meeting the diagnostic criteria of acute pancreatitis (AP)

• Age =18 years

• Systematic examination and diagnostic information were available after admission

Exclusion Criteria:

• Not the first episode of AP

• The duration of hospital stay was less than 24 hours

• Died within the first episode of AP

• A history of chronic pancreatitis or tumor

• Pregnancy

Related Conditions & MeSH terms

• Acute Pancreatitis
• Pancreatitis

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Qinghao Wang

References & Publications (2)

Banks PA, Bollen TL, Dervenis C, Gooszen HG, Johnson CD, Sarr MG, Tsiotos GG, Vege SS; Acute Pancreatitis Classification Working Group. Classification of acute pancreatitis--2012: revision of the Atlanta classification and definitions by international consensus. Gut. 2013 Jan;62(1):102-11. doi: 10.1136/gutjnl-2012-302779. Epub 2012 Oct 25. — View Citation

Johnson AEW, Bulgarelli L, Shen L, Gayles A, Shammout A, Horng S, Pollard TJ, Hao S, Moody B, Gow B, Lehman LH, Celi LA, Mark RG. MIMIC-IV, a freely accessible electronic health record dataset. Sci Data. 2023 Jan 3;10(1):1. doi: 10.1038/s41597-022-01899-x. Erratum In: Sci Data. 2023 Jan 16;10(1):31. doi: 10.1038/s41597-023-01945-2. Sci Data. 2023 Apr 18;10(1):219. doi: 10.1038/s41597-023-02136-9. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Number of Participants Who Experience Recurrent Acute Pancreatitis	Recurrent acute pancreatitis was defined as two or more confirmed episodes of acute pancreatitis, excluding chronic pancreatitis, with an interval of more than 3 months between attacks, and complete resolution of symptoms during the inter-episodic periods.	From admission to 3 years after discharge.