Acute Pancreatitis : Comparison of Various Scores in Predicting Severity and Outcome

Acute Pancreatitis Clinical Trial

Official title:

Acute Pancreatitis : Comparison of Various Scores in Predicting Severity and Outcome

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT06240338
• Other study ID #: Soh-Med-23-12-05MD
• Status: Not yet recruiting
• Start date: February 20, 2024
• Est. completion date: August 20, 2025

Study information

• Verified date: February 2024
• Source: Sohag University
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

The study will make a comparison between Various severity scoring systems that has been designed to assess the severity and predict prognosis in acute pancreatitis

Description:

the study will evaluate the relationship between homeostatic model assessment of insulin resistance , bedside index of severity score and the harmless acute pancreatitis score and prognosis of acute pancreatitis ,will compare of these scores in predicting severity of acute pancreatitis and will compare of these scores in predicting outcome of acute pancreatitis.

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 50
• Est. completion date: August 20, 2025
• Est. primary completion date: August 20, 2025
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Any patient with 18 years or above and met criteria for diagnosis of acute pancreatitis will be eligible for the study. Exclusion Criteria: -

Related Conditions & MeSH terms

• Acute Pancreatitis
• Pancreatitis

Intervention

Diagnostic Test:
• laboratory investigation and Imaging
laboratory parameters (white blood cell count,neutrophil count, lymphocyte count, hemoglobin level, platelet level, red cell distribution width (RDW) level, hematocrit (HCT), renal function, hepatic function, electrolytes, arterial blood gas, HOMA-IR) will be assessed and imaging: Abdominal ultrasonography, Abdominal CT or MRI if needed

Locations

Country	Name	City	State
n/a

Sponsors (1)

Lead Sponsor	Collaborator
Sohag University

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Comparison of various scores in predicting severity and outcome in patients with acute pancreatitis. 1.Homeostatic model assessment of insulin resistance. 2.The harmless acute pancreatitis score.	Homeostatic model assessment of insulin resistance it measure severity of insulin resistance, there is an association between insulin resistance and severity of acute pancreatitis.; It is defined as fasting glucose (mmol/L) × fasting insulin (µmol/L)/22.5] or [fasting glucose (mg/dL) × fasting insulin (µmol/L) Reference index levels is = 2. If index ? 2 indicate presence of insulin resistance; The harmless acute pancreatitis score Harmless acute pancreatitis score contains three parameters - blood urea nitrogen, levels of serum creatinine and haematocrit . The patient is classified as harmless acute pancreatitis score negative (-) if they have blood urea nitrogen <25 mg/dL, serum creatinine levels < 2 mg/dL, and haematocrit levels of <43% for males and <39.6% for females at the time of admission. The patient is considered positive (+) if any one of the above parameters is positive.	within 18 months