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Clinical Trial Summary

This open label, multicenter phase II/III study with multiple randomization phases at differents stages of AML treatment (induction, consolidation and HSCT where applicable) is designed to improve OS in younger (18 to 60 year-old) patients, with AML risk-adapted patient strategies. Within the intermediate risk AML group, optimal GvHD prophylaxis following allogeneic SCT in first CR, after either myeloablative (MAC) or reduced intensity (RIC) conditioning, will also be evaluated. With an adaptative design, this clinical trial could test up to 3 novel AML agents of interest.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT02416388
Study type Interventional
Source University Hospital, Angers
Contact Mathilde Hunault, PD
Email MaHunault@chu-angers.fr
Status Recruiting
Phase Phase 2/Phase 3
Start date January 2015

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