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The Study for CML Who Failed Prior TKIs or With T315I Mutation or Ph+ ALL Who Failed Prior TKIs or With T315I Mutation

Acute Lymphoblastic Leukemia Clinical Trial

Official title:
A Phase II Multi-center, Randomized, Open-label Study of Ponatinib in Chinese Patients With Chronic Myeloid Leukemia Who Have Failed Prior TKIs or With T315I Mutation, or Ph+ALL Who Have Failed Prior TKIs or With T315I Mutation

Clinical Trial Summary

This protocol will allow ponatinib with refractory Chronic Myeloid Leukemia or Ph+ Acute Lymphoblastic Leukemia

Clinical Trial Description

The purpose of this study is to determine the safety and efficacy of ponatinib in patients with chronic myeloid leukemia (CML) in chronic phase (CP), accelerated phase (AP) or blast phase (BP) or with Ph positive (Ph+) acute lymphoblastic leukemia (ALL) who either are resistant or intolerant to either dasatinib or nilotinib, or have the T315I mutation. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04233346
Study type Interventional
Source Otsuka Beijing Research Institute
Contact
Status Active, not recruiting
Phase Phase 2
Start date July 9, 2020
Completion date December 31, 2025
View Details
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