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Clinical Trial Summary

CAR T cells targeting CD19 have been approved for patients with relapsed or refractory ALL, failing two or more prior protocols. Several institutional-based studies with other CAR T cells targeting CD19 have demonstrated outstanding response rates in patients with refractory disease, and the ability of CAR T cells to clear CNS leukemia. Nevertheless, these cases are sparse and have never been reported collectively.

Here, we aim to retrospectively assess toxicity and long term outcome of patients treated with CAR T cells for CNS relapse of ALL.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT04158011
Study type Observational
Source Sheba Medical Center
Contact
Status Active, not recruiting
Phase
Start date November 6, 2019
Completion date January 1, 2021

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