Acute Leukemias Clinical Trial
Official title:
A Phase II Multi-center, Open Label, Randomized Study to Assess Safety and Efficacy of Two Different Schedules of Oral LDE225 in Adult Patients With Relapsed/Refractory or Untreated Elderly Patients With Acute Leukemia
The study will evaluate the efficacy, safety and tolerability of two dosing schedules of LDE225 in patients with relapsed/refractory acute leukemia or elderly patients with untreated acute leukemia.
n/a
Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Withdrawn |
NCT01479582 -
Providing Access to Cord Blood Units for Transplants
|
Phase 2 | |
| Terminated |
NCT02145039 -
Reduced Intensity Conditioning and Haploidentical Related Bone Marrow for Patients With Hematologic Diseases
|
N/A | |
| Completed |
NCT02141828 -
A Phase 1 Dose Escalation and Expanded Cohort Study of EPZ-5676 in the Treatment of Pediatric Patients With Relapsed/Refractory Leukemias Bearing a Rearrangement of the MLL Gene
|
Phase 1 | |
| Recruiting |
NCT04811560 -
A Study of JNJ-75276617 in Participants With Acute Leukemia
|
Phase 1/Phase 2 | |
| Recruiting |
NCT01919866 -
Safety Study of CD3/CD19 Depleted Haploidentical Stem Cells
|
Phase 1/Phase 2 | |
| Not yet recruiting |
NCT01339988 -
Busulfan and Cyclophosphamide Instead of Total Boby Irradiation (TBI) and Cyclophosphamide for Hematological Malignancies Hematocrit (HCT)
|
Phase 4 | |
| Not yet recruiting |
NCT05521087 -
A Study of JNJ-75276617 in Combination With Conventional Chemotherapy for Pediatric and Young Adult Participants With Relapsed/Refractory Acute Leukemias
|
Phase 1 |