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A Study of PTX-200 (Triciribine) Plus Cytarabine in Refractory or Relapsed Acute Leukemia

Acute Leukemia Clinical Trial

Official title:
A Phase I-II Study of Triciribine Phosphate Monohydrate (PTX-200) Plus Cytarabine in Refractory or Relapsed Acute Leukemia

Clinical Trial Summary

A phase I-II open label study of PTX-200 in combination with cytarabine in the treatment of relapsed or refractory acute leukemia.

Clinical Trial Description

Study design: Phase I/II study The Phase I study is open-label with four increasing dose levels for up to four 21-day cycles. Safety and activity will be evaluated at the end of each cycle. The Phase II study is open label with administration of the recommended phase dose of PTX-200 for up to four 21-day cycles. PTX-200 will be co-administered with cytarabine in both the Phase I and Phase II parts of the study. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT02930109
Study type Interventional
Source Prescient Therapeutics, Ltd.
Contact
Status Completed
Phase Phase 1/Phase 2
Start date December 9, 2016
Completion date March 4, 2024
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