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Acute Leukemia in Relapse clinical trials

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NCT ID: NCT05587088 Not yet recruiting - Clinical trials for Acute Myeloid Leukemia

Evaluation of the Safety and Efficacy of Esperanza Extract (PA001)

PA001
Start date: December 15, 2022
Phase: Phase 1/Phase 2
Study type: Interventional

This is a phase Ib/II clinical study that has two phases. In phase Ib, the safety evaluation of the extract of Petiveria alliacea (Esperanza) will be carried out in patients with metastatic gastrointestinal tumors (colon, pancreas, stomach, and biliary tract) and patients with newly diagnosed and relapsed acute leukemia. In phase IIb, the safety will continue to be evaluated, and the efficacy of the Esperanza extract will be explored in combination with chemotherapy in patients with metastatic gastrointestinal tumors (colon, pancreas, stomach, and biliary tract) with newly diagnosed acute leukemias and relapses.

NCT ID: NCT03672851 Terminated - Clinical trials for Acute Myeloid Leukemia

Study Evaluating Safety and Efficacy of CAR-T Cells Targeting CD123 in Patients With Acute Leukemia

Start date: April 17, 2019
Phase: Phase 1
Study type: Interventional

This is a single arm, open-label, phase 1 study, to determine the safety and efficacy of anti-CD123 CAR-T cells in treating patients diagnosed with refractory/relapsed acute leukemia in a dose-escalation way.