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Clinical Trial Summary

Acute graft-versus-host disease (aGVHD) is a potentially fatal complication after allogeneic hematopoietic cell transplantation (HCT), particularly for that with a HLA-mismatched donor. Abatacept has been demonstrated as a potent drug to reduce the risk of aGVHD, but the efficacy of subcutaneous form has yet been investigated. This trial is designed to preliminarily determin the efficacy and saftey of subcutaneous abatacept in the prevention of aGVHD after haplo-identical HCT.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT04686929
Study type Interventional
Source The First Affiliated Hospital of Soochow University
Contact Jia Chen, M.D.
Phone +86 512 6778 1856
Email drchenjia@163.com
Status Recruiting
Phase Phase 1/Phase 2
Start date June 1, 2021
Completion date December 30, 2023

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