Abatacept s.c. for aGVHD Prevention in Haplo-HCT

Status Recruiting

Clinical Trial Summary

Acute graft-versus-host disease (aGVHD) is a potentially fatal complication after allogeneic hematopoietic cell transplantation (HCT), particularly for that with a HLA-mismatched donor. Abatacept has been demonstrated as a potent drug to reduce the risk of aGVHD, but the efficacy of subcutaneous form has yet been investigated. This trial is designed to preliminarily determin the efficacy and saftey of subcutaneous abatacept in the prevention of aGVHD after haplo-identical HCT.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT04686929
Study type	Interventional
Source	The First Affiliated Hospital of Soochow University
Contact	Jia Chen, M.D.
Phone	+86 512 6778 1856
Email	drchenjia@163.com
Status	Recruiting
Phase	Phase 1/Phase 2
Start date	June 1, 2021
Completion date	December 30, 2023

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