Pathway and Urgent caRe of Dyspneic Patient at the Emergency Department in LorrainE District (PURPLE)

Acute Dyspnea Clinical Trial

— PURPLE  

Official title:

Pathway and Urgent caRe of Dyspneic Patient at the Emergency Department in LorrainE District

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT03194243
• Other study ID #: 2016-A01877-44
• Status: Recruiting
• Phase: N/A
• First received: May 29, 2017
• Last updated: October 9, 2017
• Start date: October 5, 2017
• Est. completion date: October 2023

Study information

• Verified date: October 2017
• Source: Central Hospital, Nancy, France
• Contact: Tahar CHOUIHED, MD
• Phone: + 33 3 83 85 14 96
• Email: t.chouihed[@]chru-nancy.fr
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

This is an observational prospective multicenter study of patients admitted for acute dyspnea in an emergency department of the participating centers in the Lorraine district.

The primary objective is to assess the outcome of this population according to the cause of acute dyspnea as well as identify the predictors of this outcome, both overall and according to each acute dyspnea cause.

Description:

This observational prospective multicenter study will be conducted using data from electronic medical records, acquired as part of usual care, in patients admitted for acute dyspnea in the emergency department. Clinical, treatment, laboratory and imaging data acquired during the hospitalization (in the emergency department and in the department that admitted the patients following the emergency department stay) will be collected.

Vital status will be recorded at 30 days and 1 year post-admission.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 75000
• Est. completion date: October 2023
• Est. primary completion date: October 2023
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Men or women > or = 18 years.

• Patients with acute dyspnea admitted for acute dyspnea in the emergency department.

• Patient informed.

Exclusion Criteria:

• Cardiorespiratory arrest.

• Patient having expressed his or her opposition.

Related Conditions & MeSH terms

• Acute Dyspnea
• Dyspnea
• Emergencies

Locations

Country	Name	City	State
France	CH EPINAL - Service des Urgences	Épinal	Lorraine
France	CH Marie-Madeleine FORBACH - Service des Urgences	Forbach	Lorraine
France	CH LUNEVILLE - Service des Urgences	Lunéville	Lorraine
France	CHR METZ-THIONVILLE- Hôpital de Mercy- Service des Urgences	Metz	Lorraine
France	CHRU Nancy - Service des Urgences	Nancy	Lorraine
France	CH PONT A MOUSSON- Service des Urgences	Pont-à-Mousson	Lorraine
France	CH REMIREMONT - Service des Urgences	Remiremont	Lorraine
France	CH SAINT-DIE-DES-VOSGES - Service des Urgences	Saint-Dié-des-Vosges	Lorraine
France	CHR METZ-THIONVILLE- Hôpital Bel-Air- Service des Urgences	Thionville	Lorraine

Sponsors (1)

Lead Sponsor	Collaborator
Central Hospital, Nancy, France

Country where clinical trial is conducted

France, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	All cause mortality		From emergency admission for acute dyspnea up until 1 year
Secondary	Demographic data		through hospital stay, an average of 10 days
Secondary	Clinical data		through hospital stay, an average of 10 days
Secondary	Treatment data		through hospital stay, an average of 10 days
Secondary	Laboratory data		through hospital stay, an average of 10 days
Secondary	Imaging data		through hospital stay, an average of 10 days
Secondary	Duration of hospitalization	including emergency stay and conventional hospitalization	At final discharge, an average of 10 days after admission
Secondary	Initial diagnosis in the emergency department		At admission
Secondary	Final diagnosis of the initial hospitalization stay		At final discharge, an average of 10 days after admission
Secondary	Brain Natriuretic Peptide		Through hospital stay, an average of 10 days
Secondary	Estimated glomerular function rate		Through hospital stay, an average of 10 days
Secondary	Estimated plasma volume		Through hospital stay, an average of 10 days
Secondary	Liver biological biomarkers		Through hospital stay, an average of 10 days
Secondary	Urea		Through hospital stay, an average of 10 days
Secondary	Use of non-invasive ventilation		Through hospital stay, an average of 10 days
Secondary	Time of use of non-invasive ventilation		Through hospital stay, an average of 10 days
Secondary	Use of diuretics		Through hospital stay, an average of 10 days
Secondary	Time of use of diuretics		Through hospital stay, an average of 10 days
Secondary	Use of nitrates		Through hospital stay, an average of 10 days
Secondary	Time of use of nitrates		Through hospital stay, an average of 10 days
Secondary	Department type admitting the patient following emergency management	intensive care unit, cardiology, cardiac intensive care unit, other ...	Through hospital stay, an average of 10 days
Secondary	All cause in-hospital mortality		At final discharge, an average of 10 days after admission