Acute Coronary Syndromes Clinical Trial
Official title:
Does Optical Coherence Tomography Optimise Results of Stenting: The DOCTORS Study
Optical Coherence Tomography (OCT) is a recent imaging modality that yields cross-sectional
images with a resolution 10 times greater than that of intravascular ultrasound (IVUS). OCT
uses a near-infra-red light source to obtain images of the interior walls of the coronary
arteries and is increasingly used to evaluate vulnerable atherosclerotic plaques and assess
placement and response to stenting. - To date, no study has evaluated whether optical
coherence tomography (OCT) contributes to optimizing percutaneous coronary intervention (PCI)
and stenting.
The DOCTORS study is a randomized, open label study to evaluate whether OCT-guided
angioplasty would provide useful clinical information beyond that obtained by angiography,
and whether this information would subsequently modify physician behavior and treatment
choices. In particular, we will evaluate the impact of changes in procedural strategy
resulting from the use of OCT on the value of fractional flow reserve (FFR) obtained after
angioplasty and stent implantation of a lesion responsible for non-ST segment elevation acute
coronary syndromes.
n/a
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT02552407 -
Thrombectomy in ST Elevation Myocardial Infarction, an Individual Patient Meta-analysis
|
N/A | |
| Completed |
NCT01398228 -
Clinical Pathways for the Management of Acute Coronary Syndromes - Phase 3,CPACS-3
|
N/A | |
| Completed |
NCT01135667 -
Prasugrel Versus Double Dose Clopidogrel to Treat Clopidogrel Low-responsiveness After PCI
|
Phase 4 | |
| Recruiting |
NCT02592720 -
Cocktail Injection Improves Outcomes of FFR Guided PCI
|
Phase 4 | |
| Completed |
NCT01641510 -
PRAsugrel or clopIdogrel In Acute Coronary SyndromE With CYP2C19 GENEtic Variants
|
Phase 3 | |
| Active, not recruiting |
NCT01433627 -
Minimizing Adverse Haemorrhagic Events by TRansradial Access Site and Systemic Implementation of angioX
|
Phase 3 | |
| Completed |
NCT01452282 -
Ankle-Brachial Index Estimating Cardiac Complications After Surgery
|
N/A | |
| Recruiting |
NCT01418794 -
Efficacy and Safety of the YUKON Drug Eluting Stent in Diffuse Coronary Artery Disease
|
Phase 4 | |
| Recruiting |
NCT01000701 -
Inflammation and Acute Coronary Syndromes
|
N/A | |
| Terminated |
NCT01107899 -
Study to Learn When Platelets Return to Normal After One Loading Dose of Anti-platelet Drugs in Patients With Symptoms of Acute Coronary Syndromes
|
Phase 1 | |
| Completed |
NCT00494247 -
Endothelial Progenitor Cells-capture Stents in Acute Coronary Syndromes
|
Phase 4 | |
| Terminated |
NCT00615719 -
Computed Tomographic Coronary Angiography for Acute Chest Pain Evaluation
|
N/A | |
| Active, not recruiting |
NCT06089343 -
High-risk Features of Coronary Lesions in CTA and OCT
|
||
| Not yet recruiting |
NCT04023630 -
DUAL Antithrombotic Therapy in Patients With AF and ACS
|
Phase 4 | |
| Recruiting |
NCT02601404 -
REal World Advanced Experience of BioResorbable ScaffolD by SMart Angioplasty Research Team (SMART REWARD)
|
N/A | |
| Completed |
NCT02195193 -
Integrating Depression Care in Acute Coronary Syndromes Care in China
|
N/A | |
| Completed |
NCT02141750 -
THIRD NATIONAL REGISTRY OF ACUTE CORONARY SYNDROMES
|
N/A | |
| Not yet recruiting |
NCT01735227 -
Omeprazole and Pantoprazole Antiplatelet Effect of Clopidogrel Clinical Trials(OPEN)
|
Phase 4 | |
| Completed |
NCT00097591 -
A Comparison of Prasugrel (CS-747) and Clopidogrel in Acute Coronary Syndrome Subjects Who Are to Undergo Percutaneous Coronary Intervention
|
Phase 3 | |
| Completed |
NCT02725099 -
Chewing Versus Traditional Oral Administration of Ticagrelor in STEMI Patients
|
Phase 4 |