Clinical Trials Logo
  1. Home
  2. Acute Chest Syndrome
  3. NCT01041339
  4. Details
NCT01041339 Clinical Trial

ST Elevation in Acute Chest Pain; Could Measurement of Lipoprotein-associated Phospholipase A2 (Lp-PLA2) be Helpful to the Clinician?

Acute Chest Syndrome Clinical Trial

Official title:
ST Elevation (Acute Coronary Syndrome Versus Pericarditis;Could Measurement of Lp-associated PLA2 -a Vascular Specific Marker of Inflammation- be Helpful to the Clinician?

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT01041339
Other study ID # 0075-09-WOMC
Secondary ID
Status Completed
Phase N/A
First received December 30, 2009
Last updated December 13, 2015
Start date January 2010
Est. completion date January 2012

Study information
Verified date June 2011
Source Wolfson Medical Center
Contact n/a
Is FDA regulated No
Health authority Israel: Ethics Commission
Study type Observational

Clinical Trial Summary

A blood test (2-3 cc peripheral venous blood) drawn /used from already available required lab tests to distinguish between pericarditis accompanied with electrocardiogram (ECG) signs mimicking infarction. A test of clinical potential if proven to be able to support either origin of acute chest pain etiology.

Description:

Too many times young patients presenting with acute chest pain are referred to invasive angiography or treated with anticoagulation therapy a measure of detrimental effect in those inflicted with acute pericarditis.

A simple blood test (the PLAC test) may have some value in aiding rapid diagnosis saving need for cath.

Recruitment information / eligibility
Status Completed
Enrollment 40
Est. completion date January 2012
Est. primary completion date November 2011
Accepts healthy volunteers Accepts Healthy Volunteers
Gender Both
Age group 18 Years to 70 Years
Eligibility Inclusion Criteria:

- acute chest pain

- acute ST elevation

- elevated troponin I

Exclusion Criteria:

- patients with recent (> 24 hour chest pain) myocardial infarction

- refusing to provide blood samples

Study Design

Observational Model: Case Control, Time Perspective: Prospective

Related Conditions & MeSH terms

Locations
Country Name City State
Israel The E.Wolfson MC Holon

Sponsors (1)
Lead Sponsor Collaborator
Alexhander Izhaki

Country where clinical trial is conducted

Israel, 

See also
  Status Clinical Trial Phase
Withdrawn NCT02630394 - A Pilot Study of Azithromycin Prophylaxis for Acute Chest Syndrome in Sickle Cell Disease Phase 1
Active, not recruiting NCT04170348 - Daily Vitamin D for Sickle-cell Respiratory Complications Phase 2
Recruiting NCT03498105 - Utility of the Cardiac Electrical BiomarkerDisease
Terminated NCT02098993 - Feasibility Study of Unfractionated Heparin in Acute Chest Syndrome Phase 2
Not yet recruiting NCT06214845 - Early-goal Directed Automated Red Blood Cell Exchange for Acute Chest Syndrome in Sickle Cell Disease N/A
Completed NCT02187445 - Inhaled Corticosteroid Use to Prevent Acute Chest Syndrome Recurrence in Children Between 1 and 4 With Sickle Cell Disease: a Feasibility Trial Phase 1
Completed NCT01089439 - Nitric Oxide Therapy for Acute Chest Syndrome in Sickle Cell Disease Children Phase 2
Completed NCT03919266 - Combined Use of a Respiratory Broad Panel Multiplex PCR and Procalcitonin to Reduce Antibiotics Exposure in Hospitalized Sickle-cell Adults With Acute Chest Syndrome. N/A
Terminated NCT01589926 - Bi-Level Positive Airway Ventilation for Acute Chest Syndrome N/A
Completed NCT03250585 - sPLA2 in EBC During Acute Chest Syndrome
Completed NCT03805581 - Defibrotide in Sickle Cell Disease-Related Acute Chest Syndrome Phase 2
Recruiting NCT03032055 - Validation of a Predictive Score of Acute Chest Syndrome
Terminated NCT03820466 - Effect of Platelet Inhibition and / or Lipid Lowering in Non-ACS-patients With Positive Troponin Phase 3
Completed NCT00748423 - Effect of Inhaled Nitric Oxide in Acute Chest Syndrome (INOSTA Study) Phase 2/Phase 3
Completed NCT00434473 - IMPACTS Trial: Investigation of the Modulation of Phospholipase in Acute Chest Syndrome Phase 2
Completed NCT02580773 - Therapeutic Anticoagulation Strategy for Acute Chest Syndrome Phase 3
Completed NCT01443728 - Vitamin D for Sickle-cell Respiratory Complications Phase 2
Recruiting NCT05640271 - Tocilizumab for Acute Chest Syndrome Phase 2

External Links