Asthma Clinical Trial
Official title:
Risk of Allergic Asthma Occurring in the Long Term From an Episode of Acute Bronchiolitis in Infants: Clinical, Allergological and Functional Evaluation in the Long Term
Predicting the risk of allergenic sensitizations and asthma development in the first year of
life is difficult.
Investigator decided to follow prospectively two cohorts of infants with acute bronchiolitis,
hospitalized or treated at home, from the epidemic seasons of 2011-2012 and 2015-2017 to know
their respiratory evolution, especially if they developed allergen sensitization and / or
asthma.
Follow-up consultation 6 years after an episode of acute bronchiolitis at Clermont-Ferrand
hospital with:
- Consultation with a pneumopediatrician: collection of respiratory symptoms, respiratory
treatments, evaluation of the atopic site and environmental risk factors for bronchial
aggression, especially passive smoking;
- Physical examination ;
- Evaluation of precariousness during the same interview with the EPICES questionnaire;
- Prick tests with positive control (histamine) and negative (physiological saline) and
prick for the main pneumallergens (mites, alternaria, grasses, cat and dog) and
trophallergens (egg, milk, fish, soy, wheat, peanut);
- Blood test with blood count, determination of specific IgE (5 pneumallergens and 5
trophallergens), dosage of sRAGE;
- Fonctionnal respiratory test with reversibility test
;
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