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Nebulized 3% Hypertonic Saline in the Treatment of Acute Bronchiolitis in the Emergency Department

Acute Bronchiolitis Clinical Trial

Official title:
Nebulized 3% Hypertonic Saline in the Treatment of Acute Bronchiolitis in the Emergency Department

Clinical Trial Summary

This is a prospective, randomized, controlled, double-blinded, clinical trial

Subject : 3mo ~ 24mo. aged infants with bronchiolitis

The effect of 3 % NaCl nebulizer or dexamethasone on admission rate of these infants in ED.

Clinical Trial Description

Randomly assigned to one of three groups

- Group I : nebulized epinephrine + 0.9% saline + placebo

- Group II : nebulized epinephrine + 3% saline + placebo

- Group III : nebulized epinephrine + 0.9% saline + dexamethasone

Group I received two treatments of nebulized epinephrine mixed 0.9% saline and a total of six oral doses of placebo, group II received nebulized epinephrine mixed 3% saline and oral placebo, and group III received nebulized epinephrine mixed 0.9% saline and oral dexamethasone.

The primary outcome is hospital admission within 7 days after the day of enrollment ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01660867
Study type Interventional
Source Seoul National University Hospital
Contact
Status Withdrawn
Phase Phase 4
Start date August 2012
Completion date December 2014
View Details
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