Acute Bronchiolitis Clinical Trial
Official title:
Nebulized 3% Hypertonic Saline in the Treatment of Acute Bronchiolitis in the Emergency Department
This is a prospective, randomized, controlled, double-blinded, clinical trial
Subject : 3mo ~ 24mo. aged infants with bronchiolitis
The effect of 3 % NaCl nebulizer or dexamethasone on admission rate of these infants in ED.
Randomly assigned to one of three groups
- Group I : nebulized epinephrine + 0.9% saline + placebo
- Group II : nebulized epinephrine + 3% saline + placebo
- Group III : nebulized epinephrine + 0.9% saline + dexamethasone
Group I received two treatments of nebulized epinephrine mixed 0.9% saline and a total of six
oral doses of placebo, group II received nebulized epinephrine mixed 3% saline and oral
placebo, and group III received nebulized epinephrine mixed 0.9% saline and oral
dexamethasone.
The primary outcome is hospital admission within 7 days after the day of enrollment
;
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Completed |
NCT01469845 -
The SABRE Trial of Hypertonic Saline in Acute Bronchiolitis
|
Phase 3 | |
| Completed |
NCT02962505 -
Continuous Regional Analysis Device for Neonate Lung
|
||
| Recruiting |
NCT02984046 -
Acute Bronchiolitis and Severity Markers: Interest in Protein CC16
|
N/A | |
| Completed |
NCT01875757 -
Effect of Supplementation With Vitamin D on the Acute Bronchitis Prevention During the First Year of Life
|
Phase 3 | |
| Completed |
NCT01871857 -
7% Hypertonic Saline for Acute Bronchiolitis
|
Phase 4 | |
| Completed |
NCT06139029 -
Comparison of 3% Normal Saline Nebulization Versus Steroid Nebulization in the Treatment of Bronchiolitis
|
Early Phase 1 | |
| Not yet recruiting |
NCT03915197 -
Acute Bronchiolitis in Infants and Allergic Asthma
|
N/A | |
| Completed |
NCT03171142 -
Effect of Heliox on RSV Bronchiolitis
|
Phase 3 | |
| Completed |
NCT04245202 -
Comparison of High Flow Nasal Cannula and Standard Face Mask Oxygen Therapy in Children With Bronchiolitis
|
N/A | |
| Not yet recruiting |
NCT06441162 -
Efficacy Of Combined Nebulized Hypertonic Saline and Chest Percussion Therapy in Acute Viral Bronchiolitis
|
Phase 4 | |
| Recruiting |
NCT02093715 -
FeNO and Cytokines in Respiratory Syncytial Virus (RSV) and Non RSV Bronchiolitis in Relation to Future Asthma
|
N/A | |
| Not yet recruiting |
NCT03880903 -
Hypertonic Saline Inhalation in Acute Bronchiolitis
|
Phase 4 | |
| Completed |
NCT04748159 -
Effects of Prone Positioning on Vital Parameters in Infants With Acute Bronchiolitis
|
N/A | |
| Active, not recruiting |
NCT04613180 -
Evaluation of the Effectiveness of Montelukast in Children With Recurrent Obstructive Bronchitis
|
Phase 4 | |
| Recruiting |
NCT06321133 -
High Flow Nasal Cannula Weaning in Acute Bronchiolitis
|
N/A | |
| Completed |
NCT02029040 -
Nebulized 3% Hypertonic Saline in the Treatment of Acute Bronchiolitis
|
N/A | |
| Recruiting |
NCT03753802 -
Evaluation of the Effects of Respiratory Physiotherapy in Infants With Moderate Acute Bronchiolitis
|
N/A |