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Acute Bronchiolitis clinical trials

View clinical trials related to Acute Bronchiolitis.

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NCT ID: NCT06441162 Not yet recruiting - Acute Bronchiolitis Clinical Trials

Efficacy Of Combined Nebulized Hypertonic Saline and Chest Percussion Therapy in Acute Viral Bronchiolitis

Start date: June 30, 2024
Phase: Phase 4
Study type: Interventional

This study will examine the efficacy of combined nebulized hypertonic saline with chest percussion therapy in patients age 0 to 24 months admitted to the general inpatient pediatrics unit with acute bronchiolitis. 3% nebulized hypertonic saline treatments combined with 3 minutes of chest percussion therapy will be administered every 6 hours of patients selected for the study.

NCT ID: NCT06321133 Recruiting - Acute Bronchiolitis Clinical Trials

High Flow Nasal Cannula Weaning in Acute Bronchiolitis

Start date: February 13, 2024
Phase: N/A
Study type: Interventional

The goal of this clinical study is to compared two different strategies to end high flow nasal cannula treatment in acute bronchiolitis. This study compared the immediate ending of high flow treatment to weaning strategy, in which the flow rate is gradually decreased. The aim is to assess if the immediate ending shortens the hospitalization time and whether it is a safe strategy.

NCT ID: NCT06139029 Completed - Acute Bronchiolitis Clinical Trials

Comparison of 3% Normal Saline Nebulization Versus Steroid Nebulization in the Treatment of Bronchiolitis

Start date: November 15, 2022
Phase: Early Phase 1
Study type: Interventional

To compare the efficacy of 3% normal saline nebulization and steroid nebulization in the treatment of bronchiolitis in infants.

NCT ID: NCT04748159 Completed - Clinical trials for Infant, Premature, Diseases

Effects of Prone Positioning on Vital Parameters in Infants With Acute Bronchiolitis

Start date: January 3, 2020
Phase: N/A
Study type: Interventional

This intervention study is designed to evaluate short-term effects (within one hour) of prone position on vital signs in infants under 12 months of age with acute RSV bronchiolitis. The primary objective is to investigate whether respiratory rate changes in prone position. Secondary endpoints are changes in oxygen saturation (SpO2), transcutaneous carbon dioxide partial pressure (pCO2), heart rate, and respiratory symptoms assessed by the Modified Tal Score (MTS).

NCT ID: NCT04613180 Active, not recruiting - Acute Bronchiolitis Clinical Trials

Evaluation of the Effectiveness of Montelukast in Children With Recurrent Obstructive Bronchitis

Start date: January 3, 2018
Phase: Phase 4
Study type: Interventional

The aim of the study was to evaluate the effectiveness of montelukast sodium in the treatment and prevention of recurrent obstructive bronchitis in children. The investigators examined 80 children aged 1 to 7 years with recurrent obstructive bronchitis, who were randomly divided into 2 groups.

NCT ID: NCT04245202 Completed - Acute Bronchiolitis Clinical Trials

Comparison of High Flow Nasal Cannula and Standard Face Mask Oxygen Therapy in Children With Bronchiolitis

Start date: March 14, 2017
Phase: N/A
Study type: Interventional

The study aims to compare the efficacy of two different oxygenation methods on decrease respiratory rate, heart rate, and clinical respiratory score in children with moderate to severe bronchiolitis requiring oxygen therapy. 1. Standard face mask oxygen therapy (St-FMOT) 2. High-flow nasal cannula oxygen therapy (HFNCOT)

NCT ID: NCT03915197 Not yet recruiting - Asthma Clinical Trials

Acute Bronchiolitis in Infants and Allergic Asthma

Start date: May 2, 2019
Phase: N/A
Study type: Interventional

Predicting the risk of allergenic sensitizations and asthma development in the first year of life is difficult. Investigator decided to follow prospectively two cohorts of infants with acute bronchiolitis, hospitalized or treated at home, from the epidemic seasons of 2011-2012 and 2015-2017 to know their respiratory evolution, especially if they developed allergen sensitization and / or asthma.

NCT ID: NCT03880903 Not yet recruiting - Acute Bronchiolitis Clinical Trials

Hypertonic Saline Inhalation in Acute Bronchiolitis

Start date: July 20, 2020
Phase: Phase 4
Study type: Interventional

Acute bronchiolitis is a viral infection that occurs in children most commonly in the first 2 years of life and is characterized by respiratory symptoms, resulting in wheezing and/or crackles upon auscultation. It is usually a self limiting illness. However, this condition may be associated with several severe complications, such as apnea,respiratory failure, or secondary bacterial infection

NCT ID: NCT03753802 Recruiting - Acute Bronchiolitis Clinical Trials

Evaluation of the Effects of Respiratory Physiotherapy in Infants With Moderate Acute Bronchiolitis

Bronkiville
Start date: December 1, 2019
Phase: N/A
Study type: Interventional

Bronchiolitis affects 460,000 children in France per year. The French study called "Bronkilib 2" found a positive effect of chest physiotherapy treatment. This study and the work done so far in chest physiotherapy prompt us to recommend respiratory physiotherapy with slow passive expiratory handlings in the treatment of the moderate bronchiolitis of infants. But, further studies are still needed to corroborate these early findings. The Cochrane is recommending new high-level proof studies on passive expiratory techniques to conclude about their benefits. The aim of this study is to evaluate the effectiveness of the bronchial drainage procedure carried out during chest physiotherapy sessions, during episodes of moderate to acute bronchiolitis in infants aged 3 to 24 months. Currently, the French High Authority for Health recommends performing physiotherapy sessions for the symptomatologic treatment of acute bronchiolitis in infants - in cases where it could be described as moderate - but few studies have demonstrated the efficacy of this treatment. The study included infants with a first or a second episode of bronchiolitis classified as moderate according to the Wang's Respiratory score. The treated group will receive chest physiotherapy treatment using slow extended and passive expiratory handlings. The control group will not receive physiotherapy treatment. The study will be conducted during 4 days. The clinical symptoms and the general health condition of the infant will be evaluate by questionnaires.

NCT ID: NCT03171142 Completed - RSV Infection Clinical Trials

Effect of Heliox on RSV Bronchiolitis

Start date: May 1, 2015
Phase: Phase 3
Study type: Interventional

Helium is an inert gas with a density almost one-seventh of that of air. Based on its properties breathing a mixture of helium and oxygen (heliox) will lead to a reduction in resistance through narrowed airways and consequently decreases the work of breathing. Participating infants with RSV acute bronchiolitis will be supplied with heliox (ration of 21 oxygen and 79 helium) delivered through a flow nasal cannula to evaluate heliox effect in improving their oxygenation. Heliox will act as an additive therapy to improve oxygenation in patients with lower respiratory tract infection caused by respiratory Syncytial Virus (RSV) and will decrease the need for more complicated therapies.