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Actinic Keratosis clinical trials

View clinical trials related to Actinic Keratosis.

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NCT ID: NCT01151956 Completed - Actinic Keratosis Clinical Trials

Imiquimod and Actinic Keratoses: an Observational Study

Start date: May 2008
Phase: N/A
Study type: Observational

Objective: To show how dermatologists treat actinic keratoses with imiquimod 5% cream in their daily clinical routine. Design: Prospective, non-interventional, observational, multicenter clinical study. Setting: Offices of 93 non hospital based Austrian dermatologists. Participants: Inclusion of the 463 patients into the study was solely based on the treatment decision of the dermatologist and the patients will. Interventions: No specific interventions except suggested time points of visits with pre-defined documentation forms. The therapy of actinic keratoses followed the imiquimod label (3x/week for 4 weeks, 4 therapy free weeks, another 3x/week for 4 weeks, when needed) Main outcome measure: Information about the typical imiquimod patient, therapeutic course, treatment decisions, safety and satisfaction of patients/dermatologists.

NCT ID: NCT01000636 Completed - Actinic Keratosis Clinical Trials

Gene Expression in Renal Transplant Patients With Field Actinic Keratosis Undergoing Metvix® Photodynamic Therapy (PDT)

Start date: October 2009
Phase: Phase 4
Study type: Interventional

The aim of this study is to determine possible molecular changes on large scale gene expression profiling after treatment with Metvix photodynamic therapy (PDT) of actinic keratoses (AK) and cancerised field in renal transplant recipients.

NCT ID: NCT00991861 Completed - Actinic Keratosis Clinical Trials

Efficacy and Safety Study of LAS41007 in the Treatment of Actinic Keratosis

Start date: August 2009
Phase: Phase 2
Study type: Interventional

The aim of this study is to determine the efficacy, safety and tolerability of either a once or twice daily topical application of LAS41007 compared to a twice daily application of LAS106521 in the treatment of actinic keratosis.

NCT ID: NCT00989313 Completed - Actinic Keratosis Clinical Trials

A Long Term Follow up Study of Patients Who Have Complete Clearance of Their Actinic Keratosis (AK) Lesions at the Day 57 Visit in the PEP005-028 Study

Start date: September 2009
Phase: Phase 3
Study type: Observational

This study is designed to follow up patients, who have participated in the PEP005-028 study and observed complete clearance of their Actinic Keratosis (AK) lesions, over a 12 month period to assess both recurrence of AK lesions and long term safety in the selected treatment area.

NCT ID: NCT00987246 Completed - Actinic Keratosis Clinical Trials

Study on the Efficacy of LAS41005 in the Treatment of Actinic Keratosis

Start date: June 2008
Phase: Phase 3
Study type: Interventional

The purpose of this study is to investigate the efficacy of LAS41005 in comparison to placebo and to LAS106521 in actinic keratosis (AK).

NCT ID: NCT00953732 Completed - Actinic Keratosis Clinical Trials

A Long Term Follow up Study of Patients Who Have Completed the PEP005-016 or PEP005-025 Studies

Start date: August 2009
Phase: Phase 3
Study type: Observational

This study is designed to follow up patients who have achieved complete clearance of AK lesions at the Day 57 visit having completed the PEP005-016 or PEP005-025 studies over a 12 month period to assess both recurrence of Actinic Keratosis (AK) lesions and long term safety in the selected treatment area.

NCT ID: NCT00952783 Completed - Actinic Keratosis Clinical Trials

A Long Term Follow up Study of Patients Who Have Completed the PEP005-020 Study

Start date: July 2009
Phase: Phase 3
Study type: Observational

This study is designed to follow up patients, who have achieved complete clearance of AK lesions (lesion count of 0) at Day 57 in the PEP005-020 study, over a 12 month period to assess both recurrence of Actinic Keratosis (AK) lesions and long term safety in the selected treatment area.

NCT ID: NCT00926952 Completed - Actinic Keratosis Clinical Trials

Short Incubation Methylaminolevulinate Photodynamic Therapy Without Occlusion

Start date: July 2009
Phase: Phase 3
Study type: Interventional

Actinic keratoses on the face are often numerous and widespread. The application of Methylaminolevulinate (MAL) on individual lesions followed by the application of a plastic film on each lesion is difficult and takes time for subjects with many actinic keratoses. The waiting period of 3 hours between MAL cream application and red light exposure is also long for patients. The goal of this study is to evaluate the safety and efficacy of photodynamic therapy (PDT) with MAL with a shorter cream application time (90 minutes) and when MAL is applied on the entire face without the plastic film.

NCT ID: NCT00917306 Completed - Actinic Keratosis Clinical Trials

A Multi-center Study to Evaluate the Safety and Efficacy of PEP005 (Ingenol Mebutate) Gel, When Used to Treat Actinic Keratoses on Non-head Locations (Trunk and Extremities)

Start date: June 2009
Phase: Phase 3
Study type: Interventional

The open label study is designed to assess the safety and efficacy of 0.05% PEP005 Gel when applied to an area of skin containing 4-8 AK lesions on non-head locations.

NCT ID: NCT00916006 Completed - Actinic Keratosis Clinical Trials

A Multi-center Study to Evaluate the Efficacy and Safety of PEP005 (Ingenol Mebutate) Gel, When Used to Treat Actinic Keratoses on the Head (Face or Scalp)

Start date: June 2009
Phase: Phase 3
Study type: Interventional

This Phase III study is designed to assess the efficacy and safety of PEP005 Gel, 0.015% when applied to an area of skin containing 4-8 AK lesions on the face or scalp.